On the relationship between persistent delay activity, repetition enhancement and priming
Human efficiency in processing incoming stimuli (in terms of speed and/or accuracy) is typically enhanced by previous exposure to the same, or closely related stimuli - a phenomenon referred to as priming. In spite of the large body of knowledge accumulated in behavioral studies about the conditions...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2015-01-01
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| Series: | Frontiers in Psychology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpsyg.2014.01590/full |
| _version_ | 1818845097388670976 |
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| author | Elisa Maria Tartaglia Elisa Maria Tartaglia Gianluigi eMongillo Nicolas eBrunel |
| author_facet | Elisa Maria Tartaglia Elisa Maria Tartaglia Gianluigi eMongillo Nicolas eBrunel |
| author_sort | Elisa Maria Tartaglia |
| collection | DOAJ |
| description | Human efficiency in processing incoming stimuli (in terms of speed and/or accuracy) is typically enhanced by previous exposure to the same, or closely related stimuli - a phenomenon referred to as priming. In spite of the large body of knowledge accumulated in behavioral studies about the conditions conducive to priming, and its relationship with other forms of memory, the underlying neuronal correlates of priming are still under debate. The idea has repeatedly been advanced that a major neuronal mechanism supporting behaviorally-expressed priming is repetition suppression, a widespread reduction of spiking activity upon stimulus repetition which has been routinely exposed by single-unit recordings in non-human primates performing delayed-response, as well as passive fixation tasks. This proposal is mainly motivated by the observation that, in human fMRI studies, priming is associated to a significant reduction of the BOLD signal (widely interpreted as a proxy of the level of spiking activity) upon stimulus repetition. Here, we critically re-examine a large part of the electrophysiological literature on repetition suppression in non-human primates and find that repetition suppression is systematically accompanied by stimulus-selective delay period activity, together with repetition enhancement, an increase of spiking activity upon stimulus repetition in small neuronal populations. We argue that repetition enhancement constitutes a more viable candidate for a putative neuronal substrate of priming, and propose a minimal framework that links together, mechanistically and functionally, repetition suppression, stimulus-selective delay activity and repetition enhancement. |
| first_indexed | 2024-12-19T05:24:14Z |
| format | Article |
| id | doaj.art-a1912c81f09649769f5a76966e1a9930 |
| institution | Directory Open Access Journal |
| issn | 1664-1078 |
| language | English |
| last_indexed | 2024-12-19T05:24:14Z |
| publishDate | 2015-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychology |
| spelling | doaj.art-a1912c81f09649769f5a76966e1a99302022-12-21T20:34:25ZengFrontiers Media S.A.Frontiers in Psychology1664-10782015-01-01510.3389/fpsyg.2014.0159091833On the relationship between persistent delay activity, repetition enhancement and primingElisa Maria Tartaglia0Elisa Maria Tartaglia1Gianluigi eMongillo2Nicolas eBrunel3IITUniversity of ChicagoUniversite' Paris Descartes- CNRSUniversity of ChicagoHuman efficiency in processing incoming stimuli (in terms of speed and/or accuracy) is typically enhanced by previous exposure to the same, or closely related stimuli - a phenomenon referred to as priming. In spite of the large body of knowledge accumulated in behavioral studies about the conditions conducive to priming, and its relationship with other forms of memory, the underlying neuronal correlates of priming are still under debate. The idea has repeatedly been advanced that a major neuronal mechanism supporting behaviorally-expressed priming is repetition suppression, a widespread reduction of spiking activity upon stimulus repetition which has been routinely exposed by single-unit recordings in non-human primates performing delayed-response, as well as passive fixation tasks. This proposal is mainly motivated by the observation that, in human fMRI studies, priming is associated to a significant reduction of the BOLD signal (widely interpreted as a proxy of the level of spiking activity) upon stimulus repetition. Here, we critically re-examine a large part of the electrophysiological literature on repetition suppression in non-human primates and find that repetition suppression is systematically accompanied by stimulus-selective delay period activity, together with repetition enhancement, an increase of spiking activity upon stimulus repetition in small neuronal populations. We argue that repetition enhancement constitutes a more viable candidate for a putative neuronal substrate of priming, and propose a minimal framework that links together, mechanistically and functionally, repetition suppression, stimulus-selective delay activity and repetition enhancement.http://journal.frontiersin.org/Journal/10.3389/fpsyg.2014.01590/fullprimingneural network modelingrepetition suppressionrepetition enhancementshort term memory |
| spellingShingle | Elisa Maria Tartaglia Elisa Maria Tartaglia Gianluigi eMongillo Nicolas eBrunel On the relationship between persistent delay activity, repetition enhancement and priming Frontiers in Psychology priming neural network modeling repetition suppression repetition enhancement short term memory |
| title | On the relationship between persistent delay activity, repetition enhancement and priming |
| title_full | On the relationship between persistent delay activity, repetition enhancement and priming |
| title_fullStr | On the relationship between persistent delay activity, repetition enhancement and priming |
| title_full_unstemmed | On the relationship between persistent delay activity, repetition enhancement and priming |
| title_short | On the relationship between persistent delay activity, repetition enhancement and priming |
| title_sort | on the relationship between persistent delay activity repetition enhancement and priming |
| topic | priming neural network modeling repetition suppression repetition enhancement short term memory |
| url | http://journal.frontiersin.org/Journal/10.3389/fpsyg.2014.01590/full |
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