Heterogeneous neural coding of corrective movements in motor cortex
During a reach, neural activity recorded from motor cortex is typically thought to linearly encode the observed movement. However, it has also been reported that during a double-step reaching paradigm, neural coding of the original movement is replaced by that of the corrective movement. Here, we...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2013-04-01
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| Series: | Frontiers in Neural Circuits |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncir.2013.00051/full |
| _version_ | 1818559374256242688 |
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| author | Adam S Dickey Yali eAmit Nicholas G Hatsopoulos |
| author_facet | Adam S Dickey Yali eAmit Nicholas G Hatsopoulos |
| author_sort | Adam S Dickey |
| collection | DOAJ |
| description | During a reach, neural activity recorded from motor cortex is typically thought to linearly encode the observed movement. However, it has also been reported that during a double-step reaching paradigm, neural coding of the original movement is replaced by that of the corrective movement. Here, we use neural data recorded from multi-electrode arrays implanted in the motor and premotor cortices of rhesus macaques to directly compare these two hypotheses. We show that while a majority of neurons display linear encoding of movement during a double-step, a minority display a dramatic drop in firing rate that is predicted by the replacement hypothesis. Neural activity in the subpopulation showing replacement is more likely to lag the observed movement, and may therefore be involved in the monitoring of the sensory consequences of a motor command. |
| first_indexed | 2024-12-14T00:24:40Z |
| format | Article |
| id | doaj.art-a191908b8a884a12970b1ef950f1fcb2 |
| institution | Directory Open Access Journal |
| issn | 1662-5110 |
| language | English |
| last_indexed | 2024-12-14T00:24:40Z |
| publishDate | 2013-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neural Circuits |
| spelling | doaj.art-a191908b8a884a12970b1ef950f1fcb22022-12-21T23:25:05ZengFrontiers Media S.A.Frontiers in Neural Circuits1662-51102013-04-01710.3389/fncir.2013.0005141507Heterogeneous neural coding of corrective movements in motor cortexAdam S Dickey0Yali eAmit1Nicholas G Hatsopoulos2University of ChicagoUniversity of ChicagoUniversity of ChicagoDuring a reach, neural activity recorded from motor cortex is typically thought to linearly encode the observed movement. However, it has also been reported that during a double-step reaching paradigm, neural coding of the original movement is replaced by that of the corrective movement. Here, we use neural data recorded from multi-electrode arrays implanted in the motor and premotor cortices of rhesus macaques to directly compare these two hypotheses. We show that while a majority of neurons display linear encoding of movement during a double-step, a minority display a dramatic drop in firing rate that is predicted by the replacement hypothesis. Neural activity in the subpopulation showing replacement is more likely to lag the observed movement, and may therefore be involved in the monitoring of the sensory consequences of a motor command.http://journal.frontiersin.org/Journal/10.3389/fncir.2013.00051/fullMotor CortexreachingNeural codingtarget jumpdouble-step |
| spellingShingle | Adam S Dickey Yali eAmit Nicholas G Hatsopoulos Heterogeneous neural coding of corrective movements in motor cortex Frontiers in Neural Circuits Motor Cortex reaching Neural coding target jump double-step |
| title | Heterogeneous neural coding of corrective movements in motor cortex |
| title_full | Heterogeneous neural coding of corrective movements in motor cortex |
| title_fullStr | Heterogeneous neural coding of corrective movements in motor cortex |
| title_full_unstemmed | Heterogeneous neural coding of corrective movements in motor cortex |
| title_short | Heterogeneous neural coding of corrective movements in motor cortex |
| title_sort | heterogeneous neural coding of corrective movements in motor cortex |
| topic | Motor Cortex reaching Neural coding target jump double-step |
| url | http://journal.frontiersin.org/Journal/10.3389/fncir.2013.00051/full |
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