Chimeric antigen receptor-engineered natural killer cells for cancer immunotherapy

Chimeric antigen receptor-engineered natural killer cells for cancer immunotherapy

Abstract Natural killer (NK) cells are a critical component of the innate immune system. Chimeric antigen receptors (CARs) re-direct NK cells toward tumor cells carrying corresponding antigens, creating major opportunities in the fight against cancer. CAR NK cells have the potential for use as unive...

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Bibliographic Details
Main Authors: Ahmet Yilmaz, Hanwei Cui, Michael A. Caligiuri, Jianhua Yu
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Journal of Hematology & Oncology
Subjects:
Chimeric antigen receptor
Natural killer cells
T cells
Cancer immunotherapy
Online Access:https://doi.org/10.1186/s13045-020-00998-9

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