Undernourished patients do not have increased risk of severe COVID-19 outcomes
Background: Undernutrition has been previously identified as a deleterious factor in acute infections. In covid-19 infection, obesity is a risk-factor of severe evolution, but initial undernutrition has not been evaluated yet. Methods: We retrospectively analyzed correlation between nutritional stat...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-08-01
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| Series: | Clinical Nutrition Open Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667268522000183 |
| _version_ | 1811215447814569984 |
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| author | Ahmad Fneich Pierre Poinsot Christelle Elias Lioara Restier Philippe Vanhems Florent Wallet Cyrielle Caussy Antoine Duclos Noël Peretti |
| author_facet | Ahmad Fneich Pierre Poinsot Christelle Elias Lioara Restier Philippe Vanhems Florent Wallet Cyrielle Caussy Antoine Duclos Noël Peretti |
| author_sort | Ahmad Fneich |
| collection | DOAJ |
| description | Background: Undernutrition has been previously identified as a deleterious factor in acute infections. In covid-19 infection, obesity is a risk-factor of severe evolution, but initial undernutrition has not been evaluated yet. Methods: We retrospectively analyzed correlation between nutritional status at admission and severe outcomes (intensive care unit admission, invasive mechanical ventilation requirement and death) of patients hospitalized for confirmed covid-19 infection. Results: Risk of intensive care unit admission and invasive mechanical ventilation requirement was not significantly different between undernutrition and normoweight sub-groups, but increased in excessive weight sub-group (ODDR (IC 95%) 1.048 (1.011-1.086), p = 0.011). Risk of death was the same in all sub-groups. Conclusion: Undernutrition didn't appear as a factor of severe outcomes in covid-19 infection. |
| first_indexed | 2024-04-12T06:22:49Z |
| format | Article |
| id | doaj.art-a195870f81ff401fa0bf98a809adad28 |
| institution | Directory Open Access Journal |
| issn | 2667-2685 |
| language | English |
| last_indexed | 2024-04-12T06:22:49Z |
| publishDate | 2022-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical Nutrition Open Science |
| spelling | doaj.art-a195870f81ff401fa0bf98a809adad282022-12-22T03:44:16ZengElsevierClinical Nutrition Open Science2667-26852022-08-0144914Undernourished patients do not have increased risk of severe COVID-19 outcomesAhmad Fneich0Pierre Poinsot1Christelle Elias2Lioara Restier3Philippe Vanhems4Florent Wallet5Cyrielle Caussy6Antoine Duclos7Noël Peretti8Univ Lyon, Hospices Civil de Lyon, Gastro-enterology and Pediatric Nutrition, Hôpital Femme Mère Enfant, F-69500, Bron, FranceUniv Lyon, Hospices Civil de Lyon, Gastro-enterology and Pediatric Nutrition, Hôpital Femme Mère Enfant, F-69500, Bron, France; Univ Lyon, CarMeN Laboratory, INRAE, UMR1397, INSERM, UMR1060, F-69310, Pierre-Bénite, France; Corresponding author. Univ Lyon, CarMeN Laboratory, INRAE, UMR1397, INSERM, UMR1060, F-69310, Pierre-Bénite, France.Emerging Pathogens Laboratory- Fondation Mérieux, Lyon, France; Univ Lyon, Centre International de Recherche en Infectiologie (CIRI), INSERM U1111, CNRS, UMR 5308, ENS Lyon, F-69008 Lyon, France; Univ Lyon, Hospices Civil de Lyon, Infection Control and Epidemiology Unit, Hôpital Croix Rousse, F-69004 Lyon, FranceUniv Lyon, Hospices Civil de Lyon, Gastro-enterology and Pediatric Nutrition, Hôpital Femme Mère Enfant, F-69500, Bron, FranceEmerging Pathogens Laboratory- Fondation Mérieux, Lyon, France; Univ Lyon, Centre International de Recherche en Infectiologie (CIRI), INSERM U1111, CNRS, UMR 5308, ENS Lyon, F-69008 Lyon, France; Univ Lyon, Hospices Civil de Lyon, Infection Control and Epidemiology Unit, Hôpital Croix Rousse, F-69004 Lyon, FranceUniv Lyon, Centre International de Recherche en Infectiologie (CIRI), INSERM U1111, CNRS, UMR 5308, ENS Lyon, F-69008 Lyon, France; Univ Lyon, Hospices Civils de Lyon, Medical Intensive Care Unit, Lyon-Sud Hospital, F69310, Pierre Bénite, FranceUniv Lyon, CarMeN Laboratory, INRAE, UMR1397, INSERM, UMR1060, F-69310, Pierre-Bénite, France; Univ Lyon, Hospices Civils de Lyon, Département Endocrinologie, Diabète et Nutrition, Hôpital Lyon Sud, F-69495, Pierre-Bénite, FranceUniv Lyon, Hospices Civils de Lyon, Health Data Department, Health Services and Performance Research Lab (HeSPeR, EA 7425), Lyon, FranceUniv Lyon, Hospices Civil de Lyon, Gastro-enterology and Pediatric Nutrition, Hôpital Femme Mère Enfant, F-69500, Bron, France; Univ Lyon, CarMeN Laboratory, INRAE, UMR1397, INSERM, UMR1060, F-69310, Pierre-Bénite, FranceBackground: Undernutrition has been previously identified as a deleterious factor in acute infections. In covid-19 infection, obesity is a risk-factor of severe evolution, but initial undernutrition has not been evaluated yet. Methods: We retrospectively analyzed correlation between nutritional status at admission and severe outcomes (intensive care unit admission, invasive mechanical ventilation requirement and death) of patients hospitalized for confirmed covid-19 infection. Results: Risk of intensive care unit admission and invasive mechanical ventilation requirement was not significantly different between undernutrition and normoweight sub-groups, but increased in excessive weight sub-group (ODDR (IC 95%) 1.048 (1.011-1.086), p = 0.011). Risk of death was the same in all sub-groups. Conclusion: Undernutrition didn't appear as a factor of severe outcomes in covid-19 infection.http://www.sciencedirect.com/science/article/pii/S2667268522000183UndernutritionCovid-19Intensive careInvasive mechanical ventilationDeath |
| spellingShingle | Ahmad Fneich Pierre Poinsot Christelle Elias Lioara Restier Philippe Vanhems Florent Wallet Cyrielle Caussy Antoine Duclos Noël Peretti Undernourished patients do not have increased risk of severe COVID-19 outcomes Clinical Nutrition Open Science Undernutrition Covid-19 Intensive care Invasive mechanical ventilation Death |
| title | Undernourished patients do not have increased risk of severe COVID-19 outcomes |
| title_full | Undernourished patients do not have increased risk of severe COVID-19 outcomes |
| title_fullStr | Undernourished patients do not have increased risk of severe COVID-19 outcomes |
| title_full_unstemmed | Undernourished patients do not have increased risk of severe COVID-19 outcomes |
| title_short | Undernourished patients do not have increased risk of severe COVID-19 outcomes |
| title_sort | undernourished patients do not have increased risk of severe covid 19 outcomes |
| topic | Undernutrition Covid-19 Intensive care Invasive mechanical ventilation Death |
| url | http://www.sciencedirect.com/science/article/pii/S2667268522000183 |
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