“Success Depends on Your Backbone”—About the Use of Polymers as Essential Materials Forming Orodispersible Films
Polymers constitute a group of materials having a wide-ranging impact on modern pharmaceutical technology. Polymeric components provide the foundation for the advancement of novel drug delivery platforms, inter alia orodispersible films. Orodispersible films are thin, polymeric scraps intended to di...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/14/17/4872 |
| _version_ | 1797521184073449472 |
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| author | Katarzyna Olechno Anna Basa Katarzyna Winnicka |
| author_facet | Katarzyna Olechno Anna Basa Katarzyna Winnicka |
| author_sort | Katarzyna Olechno |
| collection | DOAJ |
| description | Polymers constitute a group of materials having a wide-ranging impact on modern pharmaceutical technology. Polymeric components provide the foundation for the advancement of novel drug delivery platforms, inter alia orodispersible films. Orodispersible films are thin, polymeric scraps intended to dissolve quickly when put on the tongue, allowing them to be easily swallowed without the necessity of drinking water, thus eliminating the risk of choking, which is of great importance in the case of pediatric and geriatric patients. Polymers are essential excipients in designing orodispersible films, as they constitute the backbone of these drug dosage form. The type of polymer is of significant importance in obtaining the formulation of the desired quality. The polymers employed to produce orodispersible films must meet particular requirements due to their oral administration and have to provide adequate surface texture, film thickness, mechanical attributes, tensile and folding strength as well as relevant disintegration time and drug release to obtain the final product characterized by optimal pharmaceutical features. A variety of natural and synthetic polymers currently utilized in manufacturing of orodispersible films might be used alone or in a blend. The goal of the present manuscript was to present a review about polymers utilized in designing oral-dissolving films. |
| first_indexed | 2024-03-10T08:09:00Z |
| format | Article |
| id | doaj.art-a195ae847e894caba42f757fdbd7226d |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T08:09:00Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-a195ae847e894caba42f757fdbd7226d2023-11-22T10:52:55ZengMDPI AGMaterials1996-19442021-08-011417487210.3390/ma14174872“Success Depends on Your Backbone”—About the Use of Polymers as Essential Materials Forming Orodispersible FilmsKatarzyna Olechno0Anna Basa1Katarzyna Winnicka2Department of Pharmaceutical Technology, Medical University of Bialystok, Mickiewicza 2c, 15-222 Bialystok, PolandDepartment of Physical Chemistry, Faculty of Chemistry, University of Bialystok, Ciolkowskiego 1K, 15-245 Bialystok, PolandDepartment of Pharmaceutical Technology, Medical University of Bialystok, Mickiewicza 2c, 15-222 Bialystok, PolandPolymers constitute a group of materials having a wide-ranging impact on modern pharmaceutical technology. Polymeric components provide the foundation for the advancement of novel drug delivery platforms, inter alia orodispersible films. Orodispersible films are thin, polymeric scraps intended to dissolve quickly when put on the tongue, allowing them to be easily swallowed without the necessity of drinking water, thus eliminating the risk of choking, which is of great importance in the case of pediatric and geriatric patients. Polymers are essential excipients in designing orodispersible films, as they constitute the backbone of these drug dosage form. The type of polymer is of significant importance in obtaining the formulation of the desired quality. The polymers employed to produce orodispersible films must meet particular requirements due to their oral administration and have to provide adequate surface texture, film thickness, mechanical attributes, tensile and folding strength as well as relevant disintegration time and drug release to obtain the final product characterized by optimal pharmaceutical features. A variety of natural and synthetic polymers currently utilized in manufacturing of orodispersible films might be used alone or in a blend. The goal of the present manuscript was to present a review about polymers utilized in designing oral-dissolving films.https://www.mdpi.com/1996-1944/14/17/4872film-forming polymerspolymeric materialspharmaceutical excipientsorodispersible films |
| spellingShingle | Katarzyna Olechno Anna Basa Katarzyna Winnicka “Success Depends on Your Backbone”—About the Use of Polymers as Essential Materials Forming Orodispersible Films Materials film-forming polymers polymeric materials pharmaceutical excipients orodispersible films |
| title | “Success Depends on Your Backbone”—About the Use of Polymers as Essential Materials Forming Orodispersible Films |
| title_full | “Success Depends on Your Backbone”—About the Use of Polymers as Essential Materials Forming Orodispersible Films |
| title_fullStr | “Success Depends on Your Backbone”—About the Use of Polymers as Essential Materials Forming Orodispersible Films |
| title_full_unstemmed | “Success Depends on Your Backbone”—About the Use of Polymers as Essential Materials Forming Orodispersible Films |
| title_short | “Success Depends on Your Backbone”—About the Use of Polymers as Essential Materials Forming Orodispersible Films |
| title_sort | success depends on your backbone about the use of polymers as essential materials forming orodispersible films |
| topic | film-forming polymers polymeric materials pharmaceutical excipients orodispersible films |
| url | https://www.mdpi.com/1996-1944/14/17/4872 |
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