The influence of HLA/HIV genetics on the occurrence of elite controllers and a need for therapeutics geotargeting view

The influence of HLA/HIV genetics on the occurrence of elite controllers and a need for therapeutics geotargeting view

The interaction of HIV-1, human leukocyte antigen (HLA), and elite controllers (EC) compose a still intricate triad. Elite controllers maintain a very low viral load and a normal CD4 count, even without antiretrovirals. There is a lot of diversity in HIV subtypes and HLA alleles. The most common sub...

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Bibliographic Details
Main Authors: Luciano Werle Lunardi, Marcelo Alves de Souza Bragatte, Gustavo Fioravanti Vieira
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Brazilian Journal of Infectious Diseases
Subjects:
HIV
HLA class I
Elite controllers
Immunodominant epitopes
Mutation
Online Access:http://www.sciencedirect.com/science/article/pii/S141386702100088X

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