A New Predictor of Obstructive Coronary Artery Ectasia in Patients with Non-ST-Elevation Acute Coronary Syndrome: The Atherogenic Index of Plasma
Introduction: Coronary artery ectasia (CAE) is one of the uncommon cardiovascular disorders with a clinical spectrum ranging from asymptomatic cases to myocardial infarction. Atherosclerosis plays a pivotal role in the pathogenesis of CAE. Recently, it has been determined that the atherogenic index...
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| Format: | Article |
| Language: | English |
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Emergency Department of Hospital San Pedro (Logroño, Spain)
2022-09-01
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| Series: | Iberoamerican Journal of Medicine |
| Subjects: | |
| Online Access: | https://www.iberoamjmed.com/article/doi/10.53986/ibjm.2022.0039 |
| _version_ | 1797997994532929536 |
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| author | Uğur Küçük Kadir Arslan |
| author_facet | Uğur Küçük Kadir Arslan |
| author_sort | Uğur Küçük |
| collection | DOAJ |
| description | Introduction: Coronary artery ectasia (CAE) is one of the uncommon cardiovascular disorders with a clinical spectrum ranging from asymptomatic cases to myocardial infarction. Atherosclerosis plays a pivotal role in the pathogenesis of CAE. Recently, it has been determined that the atherogenic index of plasma (AIP) is a strong predictive marker for atherosclerosis. The aim of this study was to investigate whether there is a relationship between obstructive CAE and AIP in patients with non-ST segment elevation acute coronary syndrome (NSTE-ACS).
Materials and methods: In this retrospective study, hospital electronic patient records were retrospectively examined. A total of 213 NSTE-ACS patients were included in the study. Patients were divided into two groups according to non-obstructive and obstructive CAE. The AIP value was compared between groups and regression analysis evaluated whether it is an indicator to predict the risk of obstructive CAE.
Results: The AIP value was found to be numerically and statistically significant in the obstructive CAE group compared to the non-obstructive CAE group. The multivariate logistic regression analysis identified AIP as a predictor of obstructive CAE in NSTE-ACS patients in the receiver operating curve analysis, AIP values above 0.33 had 90% sensitivity and 68% specificity to predict obstructive CAE in NSTE-ACS patients.
Conclusions: AIP values were increased in the presence of obstructive CAE in NSTE-ACS patients. Our findings suggest that AIP may be involved in the pathogenesis of obstructive CAE. |
| first_indexed | 2024-04-11T10:41:30Z |
| format | Article |
| id | doaj.art-a19a96f294a04db1b64f4ec01363b755 |
| institution | Directory Open Access Journal |
| issn | 2695-5075 |
| language | English |
| last_indexed | 2024-04-11T10:41:30Z |
| publishDate | 2022-09-01 |
| publisher | Emergency Department of Hospital San Pedro (Logroño, Spain) |
| record_format | Article |
| series | Iberoamerican Journal of Medicine |
| spelling | doaj.art-a19a96f294a04db1b64f4ec01363b7552022-12-22T04:29:10ZengEmergency Department of Hospital San Pedro (Logroño, Spain)Iberoamerican Journal of Medicine2695-50752022-09-014421221910.53986/ibjm.2022.0039A New Predictor of Obstructive Coronary Artery Ectasia in Patients with Non-ST-Elevation Acute Coronary Syndrome: The Atherogenic Index of PlasmaUğur Küçük0https://orcid.org/0000-0003-4669-7387Kadir Arslan1https://orcid.org/0000-0002-7569-0179Department of Cardiology, Faculty of Medicine, Canakkale Onsekiz Mart University, Canakkale, TurkeyDepartment of Cardiology, Faculty of Medicine, Canakkale Onsekiz Mart University, Canakkale, TurkeyIntroduction: Coronary artery ectasia (CAE) is one of the uncommon cardiovascular disorders with a clinical spectrum ranging from asymptomatic cases to myocardial infarction. Atherosclerosis plays a pivotal role in the pathogenesis of CAE. Recently, it has been determined that the atherogenic index of plasma (AIP) is a strong predictive marker for atherosclerosis. The aim of this study was to investigate whether there is a relationship between obstructive CAE and AIP in patients with non-ST segment elevation acute coronary syndrome (NSTE-ACS). Materials and methods: In this retrospective study, hospital electronic patient records were retrospectively examined. A total of 213 NSTE-ACS patients were included in the study. Patients were divided into two groups according to non-obstructive and obstructive CAE. The AIP value was compared between groups and regression analysis evaluated whether it is an indicator to predict the risk of obstructive CAE. Results: The AIP value was found to be numerically and statistically significant in the obstructive CAE group compared to the non-obstructive CAE group. The multivariate logistic regression analysis identified AIP as a predictor of obstructive CAE in NSTE-ACS patients in the receiver operating curve analysis, AIP values above 0.33 had 90% sensitivity and 68% specificity to predict obstructive CAE in NSTE-ACS patients. Conclusions: AIP values were increased in the presence of obstructive CAE in NSTE-ACS patients. Our findings suggest that AIP may be involved in the pathogenesis of obstructive CAE.https://www.iberoamjmed.com/article/doi/10.53986/ibjm.2022.0039atherogenic index of plasmaangiographycoronary artery ectasiamyocardial infarction |
| spellingShingle | Uğur Küçük Kadir Arslan A New Predictor of Obstructive Coronary Artery Ectasia in Patients with Non-ST-Elevation Acute Coronary Syndrome: The Atherogenic Index of Plasma Iberoamerican Journal of Medicine atherogenic index of plasma angiography coronary artery ectasia myocardial infarction |
| title | A New Predictor of Obstructive Coronary Artery Ectasia in Patients with Non-ST-Elevation Acute Coronary Syndrome: The Atherogenic Index of Plasma |
| title_full | A New Predictor of Obstructive Coronary Artery Ectasia in Patients with Non-ST-Elevation Acute Coronary Syndrome: The Atherogenic Index of Plasma |
| title_fullStr | A New Predictor of Obstructive Coronary Artery Ectasia in Patients with Non-ST-Elevation Acute Coronary Syndrome: The Atherogenic Index of Plasma |
| title_full_unstemmed | A New Predictor of Obstructive Coronary Artery Ectasia in Patients with Non-ST-Elevation Acute Coronary Syndrome: The Atherogenic Index of Plasma |
| title_short | A New Predictor of Obstructive Coronary Artery Ectasia in Patients with Non-ST-Elevation Acute Coronary Syndrome: The Atherogenic Index of Plasma |
| title_sort | new predictor of obstructive coronary artery ectasia in patients with non st elevation acute coronary syndrome the atherogenic index of plasma |
| topic | atherogenic index of plasma angiography coronary artery ectasia myocardial infarction |
| url | https://www.iberoamjmed.com/article/doi/10.53986/ibjm.2022.0039 |
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