Efficacy of low-dose intravenous dexamethasone for prolongation of analgesia in supraclavicular block
Abstract Background Supraclavicular block is a common technique for analgesia for upper limb surgeries. Because of short duration of analgesia with bupivacaine alone various additive have been used to prolong the action of bupivacaine. We conducted a prospective, randomized, double blind controlled...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-12-01
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| Series: | Ain Shams Journal of Anesthesiology |
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| Online Access: | https://doi.org/10.1186/s42077-022-00294-3 |
| _version_ | 1797973718504308736 |
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| author | Nilesh M. Solanki Khevana P. Maheshwari |
| author_facet | Nilesh M. Solanki Khevana P. Maheshwari |
| author_sort | Nilesh M. Solanki |
| collection | DOAJ |
| description | Abstract Background Supraclavicular block is a common technique for analgesia for upper limb surgeries. Because of short duration of analgesia with bupivacaine alone various additive have been used to prolong the action of bupivacaine. We conducted a prospective, randomized, double blind controlled trial. All patients were assessed for onset and duration of sensory and motor block, and postoperative pain relief. The present study was aimed to evaluate the efficacy of intravenous dexamethasone with supraclavicular block for prolongation of analgesia in patients posted for upper limb surgeries. Results Fifty patients belonging to American Society of Anesthesiologist physical status I–II were divided into two groups (25 in each). A mixture of bupivacaine 0.5% (15 ml) + lignocaine-adrenaline 1.5% (15 ml) were given in both the groups by ultrasound guided supraclavicular block and 2 ml of IV normal saline in group C and 2 ml (8 mg) of IV dexamethasone in group D were given. The mean onset time of sensory and motor block was 8.68 ± 1.81 min and 11.12 ± 1.58 min in group D and 11 ± 2.34 min and 13.2 ± 1.65 min in group C respectively. The duration of sensory and motor block in group D (843.6 ± 62.56 and 576.8 ± 70.40) min were prolonged than to group C (281.28 ± 22.42 and 204.2 ± 12.96) min where P < 0.0001.The duration of analgesia in group D was (895.6 ± 43.98 min) as compared to group C (324.4 ± 27.36 min). At the end of 4 h, the difference of the mean VAS score was statistically significant in both the groups (P < 0.05). There was no statistically significant difference in heart rate and systolic blood pressure in both the groups. Conclusions Intravenous dexamethasone significantly prolong the duration of analgesia in supraclavicular block without the side effects. |
| first_indexed | 2024-04-11T04:08:49Z |
| format | Article |
| id | doaj.art-a19cea4560fd47e9a70362438b3ede68 |
| institution | Directory Open Access Journal |
| issn | 2090-925X |
| language | English |
| last_indexed | 2024-04-11T04:08:49Z |
| publishDate | 2022-12-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Ain Shams Journal of Anesthesiology |
| spelling | doaj.art-a19cea4560fd47e9a70362438b3ede682023-01-01T12:13:27ZengSpringerOpenAin Shams Journal of Anesthesiology2090-925X2022-12-011411710.1186/s42077-022-00294-3Efficacy of low-dose intravenous dexamethasone for prolongation of analgesia in supraclavicular blockNilesh M. Solanki0Khevana P. Maheshwari1Department of Anesthesia, B. J. Medical College and Civil HospitalDepartment of Anesthesia, B. J. Medical College and Civil HospitalAbstract Background Supraclavicular block is a common technique for analgesia for upper limb surgeries. Because of short duration of analgesia with bupivacaine alone various additive have been used to prolong the action of bupivacaine. We conducted a prospective, randomized, double blind controlled trial. All patients were assessed for onset and duration of sensory and motor block, and postoperative pain relief. The present study was aimed to evaluate the efficacy of intravenous dexamethasone with supraclavicular block for prolongation of analgesia in patients posted for upper limb surgeries. Results Fifty patients belonging to American Society of Anesthesiologist physical status I–II were divided into two groups (25 in each). A mixture of bupivacaine 0.5% (15 ml) + lignocaine-adrenaline 1.5% (15 ml) were given in both the groups by ultrasound guided supraclavicular block and 2 ml of IV normal saline in group C and 2 ml (8 mg) of IV dexamethasone in group D were given. The mean onset time of sensory and motor block was 8.68 ± 1.81 min and 11.12 ± 1.58 min in group D and 11 ± 2.34 min and 13.2 ± 1.65 min in group C respectively. The duration of sensory and motor block in group D (843.6 ± 62.56 and 576.8 ± 70.40) min were prolonged than to group C (281.28 ± 22.42 and 204.2 ± 12.96) min where P < 0.0001.The duration of analgesia in group D was (895.6 ± 43.98 min) as compared to group C (324.4 ± 27.36 min). At the end of 4 h, the difference of the mean VAS score was statistically significant in both the groups (P < 0.05). There was no statistically significant difference in heart rate and systolic blood pressure in both the groups. Conclusions Intravenous dexamethasone significantly prolong the duration of analgesia in supraclavicular block without the side effects.https://doi.org/10.1186/s42077-022-00294-3AnalgesiaDexamethasoneLocal anestheticsSupraclavicular block |
| spellingShingle | Nilesh M. Solanki Khevana P. Maheshwari Efficacy of low-dose intravenous dexamethasone for prolongation of analgesia in supraclavicular block Ain Shams Journal of Anesthesiology Analgesia Dexamethasone Local anesthetics Supraclavicular block |
| title | Efficacy of low-dose intravenous dexamethasone for prolongation of analgesia in supraclavicular block |
| title_full | Efficacy of low-dose intravenous dexamethasone for prolongation of analgesia in supraclavicular block |
| title_fullStr | Efficacy of low-dose intravenous dexamethasone for prolongation of analgesia in supraclavicular block |
| title_full_unstemmed | Efficacy of low-dose intravenous dexamethasone for prolongation of analgesia in supraclavicular block |
| title_short | Efficacy of low-dose intravenous dexamethasone for prolongation of analgesia in supraclavicular block |
| title_sort | efficacy of low dose intravenous dexamethasone for prolongation of analgesia in supraclavicular block |
| topic | Analgesia Dexamethasone Local anesthetics Supraclavicular block |
| url | https://doi.org/10.1186/s42077-022-00294-3 |
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