Characterization of the adiponectin promoter + Cre recombinase insertion in the Tg(Adipoq-cre)1Evdr mouse by targeted locus amplification and droplet digital PCR

Characterization of the adiponectin promoter + Cre recombinase insertion in the Tg(Adipoq-cre)1Evdr mouse by targeted locus amplification and droplet digital PCR

The Tg(Adipoq-cre)1Evdr mouse has become an important tool in adipose tissue biology. However, the exact genomic transgene integration site has not been established. Using Targeted Locus Amplification (TLA) we found the transgene had integrated on mouse chromosome 9 between exons 6 and 7 of Tbx18. W...

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Bibliographic Details
Main Authors:	Adrian M. Wong, Tushar P. Patel, Elizabeth K. Altman, Nicol Tugarinov, Giampaolo Trivellin, Jack A. Yanovski
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2021-01-01
Series:	Adipocyte
Subjects:	adiponectin adipose tissue tissue-specific gene expression insertion point transgenic mouse adipocyte
Online Access:	http://dx.doi.org/10.1080/21623945.2020.1861728

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