Impact of the COVID‐19 Pandemic on Diabetes‐Related Cardiovascular Mortality in the United States

Background In the past few decades, diabetes‐related cardiovascular mortality has been steadily declining. However, the impact of the COVID19 pandemic on this trend has not been previously defined. Methods and Results Diabetes‐related cardiovascular mortality data were extracted for each year betwee...

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Main Authors: Hussein Bashar, Ofer Kobo, Kamlesh Khunti, Louise Y. Sun, Martin K. Rutter, Nicholas W. S. Chew, Nick Curzen, Mamas A. Mamas
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.028896
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author Hussein Bashar
Ofer Kobo
Kamlesh Khunti
Louise Y. Sun
Martin K. Rutter
Nicholas W. S. Chew
Nick Curzen
Mamas A. Mamas
author_facet Hussein Bashar
Ofer Kobo
Kamlesh Khunti
Louise Y. Sun
Martin K. Rutter
Nicholas W. S. Chew
Nick Curzen
Mamas A. Mamas
author_sort Hussein Bashar
collection DOAJ
description Background In the past few decades, diabetes‐related cardiovascular mortality has been steadily declining. However, the impact of the COVID19 pandemic on this trend has not been previously defined. Methods and Results Diabetes‐related cardiovascular mortality data were extracted for each year between 1999 and 2020 from the Centers for Disease Control and Prevention Wide‐Ranging Online Data for Epidemiologic Research (WONDER) database. Regression analysis was used to calculate the trend in the 2 decades before the pandemic (1999–2019) and thereby estimate the excess cardiovascular mortality in 2020. There was a 29.2% fall in the diabetes‐related cardiovascular age‐adjusted mortality rate between 1999 to 2019, largely driven by a 41% decrease in ischemic heart disease deaths. In comparison to 2019, there was an overall 15.5% increase in the diabetes‐related cardiovascular age‐adjusted mortality rate in the first year of the pandemic, mainly due to a 14.1% rise in ischemic heart disease deaths. Younger patients (under 55 years) and the Black population experienced the greatest increase in diabetes‐related cardiovascular age‐adjusted mortality rate (24.0% and 25.3%, respectively). Trend analysis estimated 16 009 excess diabetes‐related cardiovascular deaths in 2020, with the majority due to ischemic heart disease (8504). Black and Hispanic or Latino populations had at least one‐fifth of their 2020 diabetes‐related cardiovascular age‐adjusted mortality rate as excess deaths (22.3% and 20.2%, respectively). Conclusions There was a sharp rise in diabetes‐related cardiovascular mortality during the first pandemic year. Black, Hispanic or Latino, and young people showed the largest increases in diabetes‐related cardiovascular mortality. Targeted health policies could help address the disparities observed in this analysis.
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spelling doaj.art-a1a86bd15a634711a512c8cdcecc236e2024-01-31T11:31:17ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802023-07-01121310.1161/JAHA.122.028896Impact of the COVID‐19 Pandemic on Diabetes‐Related Cardiovascular Mortality in the United StatesHussein Bashar0Ofer Kobo1Kamlesh Khunti2Louise Y. Sun3Martin K. Rutter4Nicholas W. S. Chew5Nick Curzen6Mamas A. Mamas7Faculty of Medicine University of Southampton United KingdomKeele Cardiovascular Research Group, Centre for Prognosis Research Institute for Primary Care and Health Sciences, Keele University Stoke‐on‐Trent United KingdomDiabetes Research Centre University of Leicester Leicester United KingdomDepartment of Anesthesiology, Perioperative and Pain Medicine Stanford University School of Medicine Palo Alto CA USADivision of Diabetes, Endocrinology and Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health University of Manchester Manchester United KingdomDepartment of Cardiology National University Heart Centre, National University Health System SingaporeFaculty of Medicine University of Southampton United KingdomKeele Cardiovascular Research Group, Centre for Prognosis Research Institute for Primary Care and Health Sciences, Keele University Stoke‐on‐Trent United KingdomBackground In the past few decades, diabetes‐related cardiovascular mortality has been steadily declining. However, the impact of the COVID19 pandemic on this trend has not been previously defined. Methods and Results Diabetes‐related cardiovascular mortality data were extracted for each year between 1999 and 2020 from the Centers for Disease Control and Prevention Wide‐Ranging Online Data for Epidemiologic Research (WONDER) database. Regression analysis was used to calculate the trend in the 2 decades before the pandemic (1999–2019) and thereby estimate the excess cardiovascular mortality in 2020. There was a 29.2% fall in the diabetes‐related cardiovascular age‐adjusted mortality rate between 1999 to 2019, largely driven by a 41% decrease in ischemic heart disease deaths. In comparison to 2019, there was an overall 15.5% increase in the diabetes‐related cardiovascular age‐adjusted mortality rate in the first year of the pandemic, mainly due to a 14.1% rise in ischemic heart disease deaths. Younger patients (under 55 years) and the Black population experienced the greatest increase in diabetes‐related cardiovascular age‐adjusted mortality rate (24.0% and 25.3%, respectively). Trend analysis estimated 16 009 excess diabetes‐related cardiovascular deaths in 2020, with the majority due to ischemic heart disease (8504). Black and Hispanic or Latino populations had at least one‐fifth of their 2020 diabetes‐related cardiovascular age‐adjusted mortality rate as excess deaths (22.3% and 20.2%, respectively). Conclusions There was a sharp rise in diabetes‐related cardiovascular mortality during the first pandemic year. Black, Hispanic or Latino, and young people showed the largest increases in diabetes‐related cardiovascular mortality. Targeted health policies could help address the disparities observed in this analysis.https://www.ahajournals.org/doi/10.1161/JAHA.122.028896cardiovascular mortalityCOVID‐19diabetesischemic heart diseaseracial disparities
spellingShingle Hussein Bashar
Ofer Kobo
Kamlesh Khunti
Louise Y. Sun
Martin K. Rutter
Nicholas W. S. Chew
Nick Curzen
Mamas A. Mamas
Impact of the COVID‐19 Pandemic on Diabetes‐Related Cardiovascular Mortality in the United States
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
cardiovascular mortality
COVID‐19
diabetes
ischemic heart disease
racial disparities
title Impact of the COVID‐19 Pandemic on Diabetes‐Related Cardiovascular Mortality in the United States
title_full Impact of the COVID‐19 Pandemic on Diabetes‐Related Cardiovascular Mortality in the United States
title_fullStr Impact of the COVID‐19 Pandemic on Diabetes‐Related Cardiovascular Mortality in the United States
title_full_unstemmed Impact of the COVID‐19 Pandemic on Diabetes‐Related Cardiovascular Mortality in the United States
title_short Impact of the COVID‐19 Pandemic on Diabetes‐Related Cardiovascular Mortality in the United States
title_sort impact of the covid 19 pandemic on diabetes related cardiovascular mortality in the united states
topic cardiovascular mortality
COVID‐19
diabetes
ischemic heart disease
racial disparities
url https://www.ahajournals.org/doi/10.1161/JAHA.122.028896
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