JMJD3 regulate H3K27me3 modification via interacting directly with TET1 to affect spermatogonia self-renewal and proliferation

JMJD3 regulate H3K27me3 modification via interacting directly with TET1 to affect spermatogonia self-renewal and proliferation

Abstract Background In epigenetic modification, histone modification and DNA methylation coordinate the regulation of spermatogonium. Not only can methylcytosine dioxygenase 1 (TET1) function as a DNA demethylase, converting 5-methylcytosine to 5-hydroxymethylcytosine, it can also form complexes wit...

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Bibliographic Details
Main Authors: Jin Wang, Lingling Liu, Zebin Li, Haoyu Wang, Yuanyuan Ren, Kaisheng Wang, Yang Liu, Xinjie Tao, Liming Zheng
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Genomics
Subjects:
Spermatogonia
TET1
JMJD3
H3K27me3
Pramel3
Online Access:https://doi.org/10.1186/s12864-024-10120-9

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