Broadly Applicable Control Approaches Improve Accuracy of ChIP-Seq Data

Chromatin ImmunoPrecipitation (ChIP) is a widely used method for the analysis of protein–DNA interactions in vivo; however, ChIP has pitfalls, particularly false-positive signal enrichment that permeates the data. We have developed a new approach to control for non-specific enrichment in ChIP that i...

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Bibliographic Details
Main Authors: Meghan V. Petrie, Yiwei He, Yan Gan, Andrew Zachary Ostrow, Oscar M. Aparicio
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/11/9271