Optofluidic Particle Manipulation: Optical Trapping in a Thin-Membrane Microchannel
We demonstrate an optofluidic device which utilizes the optical scattering and gradient forces for particle trapping in microchannels featuring 300 nm thick membranes. On-chip waveguides are used to direct light into microfluidic trapping channels. Radiation pressure is used to push particles into a...
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| Fformat: | Erthygl |
| Iaith: | English |
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MDPI AG
2022-08-01
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| Cyfres: | Biosensors |
| Pynciau: | |
| Mynediad Ar-lein: | https://www.mdpi.com/2079-6374/12/9/690 |
| _version_ | 1827662989101105152 |
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| author | Zachary J. Walker Tanner Wells Ethan Belliston Seth B. Walker Carson Zeller Mohammad Julker Neyen Sampad S. M. Saiduzzaman Holger Schmidt Aaron R. Hawkins |
| author_facet | Zachary J. Walker Tanner Wells Ethan Belliston Seth B. Walker Carson Zeller Mohammad Julker Neyen Sampad S. M. Saiduzzaman Holger Schmidt Aaron R. Hawkins |
| author_sort | Zachary J. Walker |
| collection | DOAJ |
| description | We demonstrate an optofluidic device which utilizes the optical scattering and gradient forces for particle trapping in microchannels featuring 300 nm thick membranes. On-chip waveguides are used to direct light into microfluidic trapping channels. Radiation pressure is used to push particles into a protrusion cavity, isolating the particles from liquid flow. Two different designs are presented: the first exclusively uses the optical scattering force for particle manipulation, and the second uses both scattering and gradient forces. Trapping performance is modeled for both cases. The first design, referred to as the orthogonal force design, is shown to have a 80% capture efficiency under typical operating conditions. The second design, referred to as the gradient force design, is shown to have 98% efficiency under the same conditions. |
| first_indexed | 2024-03-10T00:35:36Z |
| format | Article |
| id | doaj.art-a1b05f17a22b48c8ad4bd5b51de56f5e |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-10T00:35:36Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-a1b05f17a22b48c8ad4bd5b51de56f5e2023-11-23T15:17:30ZengMDPI AGBiosensors2079-63742022-08-0112969010.3390/bios12090690Optofluidic Particle Manipulation: Optical Trapping in a Thin-Membrane MicrochannelZachary J. Walker0Tanner Wells1Ethan Belliston2Seth B. Walker3Carson Zeller4Mohammad Julker Neyen Sampad5S. M. Saiduzzaman6Holger Schmidt7Aaron R. Hawkins8Department of Electrical and Computer Engineering, Brigham Young University, Provo, UT 84602, USADepartment of Electrical and Computer Engineering, Brigham Young University, Provo, UT 84602, USADepartment of Electrical and Computer Engineering, Brigham Young University, Provo, UT 84602, USADepartment of Electrical and Computer Engineering, Brigham Young University, Provo, UT 84602, USADepartment of Electrical and Computer Engineering, Brigham Young University, Provo, UT 84602, USASchool of Engineering, University of California, Santa Cruz, CA 95064, USASchool of Engineering, University of California, Santa Cruz, CA 95064, USASchool of Engineering, University of California, Santa Cruz, CA 95064, USADepartment of Electrical and Computer Engineering, Brigham Young University, Provo, UT 84602, USAWe demonstrate an optofluidic device which utilizes the optical scattering and gradient forces for particle trapping in microchannels featuring 300 nm thick membranes. On-chip waveguides are used to direct light into microfluidic trapping channels. Radiation pressure is used to push particles into a protrusion cavity, isolating the particles from liquid flow. Two different designs are presented: the first exclusively uses the optical scattering force for particle manipulation, and the second uses both scattering and gradient forces. Trapping performance is modeled for both cases. The first design, referred to as the orthogonal force design, is shown to have a 80% capture efficiency under typical operating conditions. The second design, referred to as the gradient force design, is shown to have 98% efficiency under the same conditions.https://www.mdpi.com/2079-6374/12/9/690lab-on-a-chipbiosensornanoporeoptofluidicmicrofluidicgradient force |
| spellingShingle | Zachary J. Walker Tanner Wells Ethan Belliston Seth B. Walker Carson Zeller Mohammad Julker Neyen Sampad S. M. Saiduzzaman Holger Schmidt Aaron R. Hawkins Optofluidic Particle Manipulation: Optical Trapping in a Thin-Membrane Microchannel Biosensors lab-on-a-chip biosensor nanopore optofluidic microfluidic gradient force |
| title | Optofluidic Particle Manipulation: Optical Trapping in a Thin-Membrane Microchannel |
| title_full | Optofluidic Particle Manipulation: Optical Trapping in a Thin-Membrane Microchannel |
| title_fullStr | Optofluidic Particle Manipulation: Optical Trapping in a Thin-Membrane Microchannel |
| title_full_unstemmed | Optofluidic Particle Manipulation: Optical Trapping in a Thin-Membrane Microchannel |
| title_short | Optofluidic Particle Manipulation: Optical Trapping in a Thin-Membrane Microchannel |
| title_sort | optofluidic particle manipulation optical trapping in a thin membrane microchannel |
| topic | lab-on-a-chip biosensor nanopore optofluidic microfluidic gradient force |
| url | https://www.mdpi.com/2079-6374/12/9/690 |
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