Novel Antidepressant Mechanism of Ginsenoside Rg1 in Regulating the Dysfunction of the Glutamatergic System in Astrocytes

Novel Antidepressant Mechanism of Ginsenoside Rg1 in Regulating the Dysfunction of the Glutamatergic System in Astrocytes

Ginsenoside Rg1, a traditional Chinese medicine monomer, has been shown to have antidepressant effects. We previously found that Rg1 exerts antidepressant effects by improving the gap junction channels (GJCs) dysfunction; however, the downstream mechanisms through which Rg1 ameliorates GJC dysfuncti...

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Bibliographic Details
Main Authors: Ningning Zhang, Hong Jiang, Huiqin Wang, Yating Wang, Ye Peng, Yangbo Liu, Congyuan Xia, Xu Yan, Shifeng Chu, Yi Zhang, Zhenzhen Wang, Naihong Chen
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
astrocytes
Cx43
ginsenoside Rg1
depression
glutamate
gap junction channel
Online Access:https://www.mdpi.com/1422-0067/24/1/575

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