Centromere mechanical maturation during mammalian cell mitosis

During mitosis, tension at the centromere occurs from the spindle but the role of centromere mechanics in controlling metaphase tension is poorly understood. Here, the authors report that mechanical stiffnness of the centromere matures during mitotic progression and is amplified specifically at meta...

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Hlavní autoři: Lauren A. Harasymiw, Damien Tank, Mark McClellan, Neha Panigrahy, Melissa K. Gardner
Médium: Článek
Jazyk:English
Vydáno: Nature Portfolio 2019-04-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/s41467-019-09578-z