Lifestyle factors and risk of sickness absence from work: a multicohort study

Summary: Background: Lifestyle factors influence the risk of morbidity and mortality, but the extent to which they are associated with employees' absence from work due to illness is unclear. We examined the relative contributions of smoking, alcohol consumption, high body-mass index, and low p...

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Main Authors: Marianna Virtanen, ProfPhD, Jenni Ervasti, PhD, Jenny Head, ProfMSc, Tuula Oksanen, MD, Paula Salo, ProfPhD, Jaana Pentti, MSc, Anne Kouvonen, ProfPhD, Ari Väänänen, ProfPhD, Sakari Suominen, ProfMD, Markku Koskenvuo, ProfMD, Jussi Vahtera, ProfMD, Marko Elovainio, ProfPhD, Marie Zins, MD, Marcel Goldberg, ProfMD, Mika Kivimäki, ProfFMedSci
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:The Lancet Public Health
Online Access:http://www.sciencedirect.com/science/article/pii/S2468266718302019
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author Marianna Virtanen, ProfPhD
Jenni Ervasti, PhD
Jenny Head, ProfMSc
Tuula Oksanen, MD
Paula Salo, ProfPhD
Jaana Pentti, MSc
Anne Kouvonen, ProfPhD
Ari Väänänen, ProfPhD
Sakari Suominen, ProfMD
Markku Koskenvuo, ProfMD
Jussi Vahtera, ProfMD
Marko Elovainio, ProfPhD
Marie Zins, MD
Marcel Goldberg, ProfMD
Mika Kivimäki, ProfFMedSci
author_facet Marianna Virtanen, ProfPhD
Jenni Ervasti, PhD
Jenny Head, ProfMSc
Tuula Oksanen, MD
Paula Salo, ProfPhD
Jaana Pentti, MSc
Anne Kouvonen, ProfPhD
Ari Väänänen, ProfPhD
Sakari Suominen, ProfMD
Markku Koskenvuo, ProfMD
Jussi Vahtera, ProfMD
Marko Elovainio, ProfPhD
Marie Zins, MD
Marcel Goldberg, ProfMD
Mika Kivimäki, ProfFMedSci
author_sort Marianna Virtanen, ProfPhD
collection DOAJ
description Summary: Background: Lifestyle factors influence the risk of morbidity and mortality, but the extent to which they are associated with employees' absence from work due to illness is unclear. We examined the relative contributions of smoking, alcohol consumption, high body-mass index, and low physical activity to diagnosis-specific sickness absence. Methods: We did a multicohort study with individual-level data of participants of four cohorts from the UK, France, and Finland. Participants' responses to a lifestyle survey were linked to records of sickness absence episodes, typically lasting longer than 9 days; for each diagnostic category, the outcome was the total number of sickness absence days per year. We estimated the associations between lifestyle factors and sickness absence by calculating rate ratios for the number of sickness absence days per year and combining cohort-specific estimates with meta-analysis. The criteria for assessing the evidence included the strength of association, consistency across cohorts, robustness to adjustments and multiple testing, and impact assessment by use of population attributable fractions (PAF), with both internal lifestyle factor prevalence estimates and those obtained from European populations (PAFexternal). Findings: For 74 296 participants, during 446 478 person-years at risk, the most common diagnoses for sickness absence were musculoskeletal diseases (70·9 days per 10 person-years), depressive disorders (26·5 days per 10 person-years), and external causes (such as injuries and poisonings; 12·8 days per 10 person-years). Being overweight (rate ratio [adjusted for age, sex, socioeconomic status, and chronic disease at baseline] 1·30, 95% CI 1·21–1·40; PAFexternal 8·9%) and low physical activity (1·23, 1·14–1·34; 7·8%) were associated with absences due to musculoskeletal diseases; heavy episodic drinking (1·90, 1·41–2·56; 15·2%), smoking (1·70, 1·42–2·03; 11·8%), low physical activity (1·67, 1·42–1·96; 19·8%), and obesity (1·38, 1·11–1·71; 5·6%) were associated with absences due to depressive disorders; heavy episodic drinking (1·64, 1·33–2·03; 11·3%), obesity (1·48, 1·27–1·72; 6·6%), smoking (1·35, 1·20–1·53; 6·3%), and being overweight (1·20, 1·08–1·33; 6·2%) were associated with absences due to external causes; obesity (1·82, 1·40–2·36; 11·0%) and smoking (1·60, 1·30–1·98; 10·3%) were associated with absences due to circulatory diseases; low physical activity (1·37, 1·25–1·49; 12·0%) and smoking (1·27, 1·16–1·40; 4·9%) were associated with absences due to respiratory diseases; and obesity (1·67, 1·34–2·07; 9·7%) was associated with absences due to digestive diseases. Interpretation: Lifestyle factors are associated with sickness absence due to several diseases, but observational data cannot determine the nature of these associations. Future studies should investigate the cost-effectiveness of lifestyle interventions aimed at reducing sickness absence and the use of information on lifestyle for identifying groups at risk. Funding: NordForsk, British Medical Research Council, Academy of Finland, Helsinki Institute of Life Sciences, and Economic and Social Research Council.
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spelling doaj.art-a1b46ef3fa024651b3109ac92f364fb52022-12-22T03:04:31ZengElsevierThe Lancet Public Health2468-26672018-11-01311e545e554Lifestyle factors and risk of sickness absence from work: a multicohort studyMarianna Virtanen, ProfPhD0Jenni Ervasti, PhD1Jenny Head, ProfMSc2Tuula Oksanen, MD3Paula Salo, ProfPhD4Jaana Pentti, MSc5Anne Kouvonen, ProfPhD6Ari Väänänen, ProfPhD7Sakari Suominen, ProfMD8Markku Koskenvuo, ProfMD9Jussi Vahtera, ProfMD10Marko Elovainio, ProfPhD11Marie Zins, MD12Marcel Goldberg, ProfMD13Mika Kivimäki, ProfFMedSci14Department of Public Health and Caring Sciences, University of Uppsala, Uppsala, Sweden; Finnish Institute of Occupational Health, Helsinki and Turku, Finland; Correspondence to: Prof Marianna Virtanen, Department of Public Health and Caring Sciences, University of Uppsala, 752 37 Uppsala, SwedenFinnish Institute of Occupational Health, Helsinki and Turku, FinlandDepartment of Epidemiology and Public Health, University College London, London, UKFinnish Institute of Occupational Health, Helsinki and Turku, FinlandFinnish Institute of Occupational Health, Helsinki and Turku, Finland; Department of Psychology, University of Turku, Turku, FinlandDepartment of Public Health, University of Turku and Turku University Hospital, Turku, FinlandFaculty of Social Sciences, University of Helsinki, Helsinki, Finland; SWPS University of Social Sciences and Humanities, Wroclaw, PolandFinnish Institute of Occupational Health, Helsinki and Turku, Finland; School of Social Policy, Sociology and Social Research, University of Kent, UKDepartment of Public Health, University of Turku and Turku University Hospital, Turku, Finland; University of Skövde, Skövde, Sweden; Folkhälsan Research Center, Helsinki, FinlandClinicum, Faculty of Medicine, University of Helsinki, FinlandDepartment of Public Health, University of Turku and Turku University Hospital, Turku, FinlandDepartment of Psychology and Logopedics, University of Helsinki, Helsinki, Finland; National Institute for Health and Welfare, Helsinki, FinlandInserm, Population-based Epidemiologic Cohorts Unit UMS 011, Villejuif, France; Paris Descartes University, Paris, FranceInserm, Population-based Epidemiologic Cohorts Unit UMS 011, Villejuif, France; Paris Descartes University, Paris, FranceDepartment of Epidemiology and Public Health, University College London, London, UK; Clinicum, Faculty of Medicine, University of Helsinki, FinlandSummary: Background: Lifestyle factors influence the risk of morbidity and mortality, but the extent to which they are associated with employees' absence from work due to illness is unclear. We examined the relative contributions of smoking, alcohol consumption, high body-mass index, and low physical activity to diagnosis-specific sickness absence. Methods: We did a multicohort study with individual-level data of participants of four cohorts from the UK, France, and Finland. Participants' responses to a lifestyle survey were linked to records of sickness absence episodes, typically lasting longer than 9 days; for each diagnostic category, the outcome was the total number of sickness absence days per year. We estimated the associations between lifestyle factors and sickness absence by calculating rate ratios for the number of sickness absence days per year and combining cohort-specific estimates with meta-analysis. The criteria for assessing the evidence included the strength of association, consistency across cohorts, robustness to adjustments and multiple testing, and impact assessment by use of population attributable fractions (PAF), with both internal lifestyle factor prevalence estimates and those obtained from European populations (PAFexternal). Findings: For 74 296 participants, during 446 478 person-years at risk, the most common diagnoses for sickness absence were musculoskeletal diseases (70·9 days per 10 person-years), depressive disorders (26·5 days per 10 person-years), and external causes (such as injuries and poisonings; 12·8 days per 10 person-years). Being overweight (rate ratio [adjusted for age, sex, socioeconomic status, and chronic disease at baseline] 1·30, 95% CI 1·21–1·40; PAFexternal 8·9%) and low physical activity (1·23, 1·14–1·34; 7·8%) were associated with absences due to musculoskeletal diseases; heavy episodic drinking (1·90, 1·41–2·56; 15·2%), smoking (1·70, 1·42–2·03; 11·8%), low physical activity (1·67, 1·42–1·96; 19·8%), and obesity (1·38, 1·11–1·71; 5·6%) were associated with absences due to depressive disorders; heavy episodic drinking (1·64, 1·33–2·03; 11·3%), obesity (1·48, 1·27–1·72; 6·6%), smoking (1·35, 1·20–1·53; 6·3%), and being overweight (1·20, 1·08–1·33; 6·2%) were associated with absences due to external causes; obesity (1·82, 1·40–2·36; 11·0%) and smoking (1·60, 1·30–1·98; 10·3%) were associated with absences due to circulatory diseases; low physical activity (1·37, 1·25–1·49; 12·0%) and smoking (1·27, 1·16–1·40; 4·9%) were associated with absences due to respiratory diseases; and obesity (1·67, 1·34–2·07; 9·7%) was associated with absences due to digestive diseases. Interpretation: Lifestyle factors are associated with sickness absence due to several diseases, but observational data cannot determine the nature of these associations. Future studies should investigate the cost-effectiveness of lifestyle interventions aimed at reducing sickness absence and the use of information on lifestyle for identifying groups at risk. Funding: NordForsk, British Medical Research Council, Academy of Finland, Helsinki Institute of Life Sciences, and Economic and Social Research Council.http://www.sciencedirect.com/science/article/pii/S2468266718302019
spellingShingle Marianna Virtanen, ProfPhD
Jenni Ervasti, PhD
Jenny Head, ProfMSc
Tuula Oksanen, MD
Paula Salo, ProfPhD
Jaana Pentti, MSc
Anne Kouvonen, ProfPhD
Ari Väänänen, ProfPhD
Sakari Suominen, ProfMD
Markku Koskenvuo, ProfMD
Jussi Vahtera, ProfMD
Marko Elovainio, ProfPhD
Marie Zins, MD
Marcel Goldberg, ProfMD
Mika Kivimäki, ProfFMedSci
Lifestyle factors and risk of sickness absence from work: a multicohort study
The Lancet Public Health
title Lifestyle factors and risk of sickness absence from work: a multicohort study
title_full Lifestyle factors and risk of sickness absence from work: a multicohort study
title_fullStr Lifestyle factors and risk of sickness absence from work: a multicohort study
title_full_unstemmed Lifestyle factors and risk of sickness absence from work: a multicohort study
title_short Lifestyle factors and risk of sickness absence from work: a multicohort study
title_sort lifestyle factors and risk of sickness absence from work a multicohort study
url http://www.sciencedirect.com/science/article/pii/S2468266718302019
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