Phosphoinositide regulation of integrin trafficking required for muscle attachment and maintenance.

Phosphoinositide regulation of integrin trafficking required for muscle attachment and maintenance.

Muscles must maintain cell compartmentalization when remodeled during development and use. How spatially restricted adhesions are regulated with muscle remodeling is largely unexplored. We show that the myotubularin (mtm) phosphoinositide phosphatase is required for integrin-mediated myofiber attach...

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Bibliographic Details
Main Authors: Inês Ribeiro, Lin Yuan, Guy Tanentzapf, James J Dowling, Amy Kiger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3037412?pdf=render

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