Melatonin Protects the Apoptosis of Sheep Granulosa Cells by Suppressing Oxidative Stress via MAP3K8 and FOS Pathway

Melatonin Protects the Apoptosis of Sheep Granulosa Cells by Suppressing Oxidative Stress via MAP3K8 and FOS Pathway

Melatonin is not only a highly effective active oxygen scavenger but also an important reproductive hormone. Melatonin has a regulatory effect on animal reproduction, especially on the ovaries. It can affect the proliferation and apoptosis of cells in follicles. However, the mechanisms of the dual a...

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Bibliographic Details
Main Authors: Bo Zhai, Xu Li, Zhongli Zhao, Yang Cao, Xinxin Liu, Zheng Liu, Huihai Ma, Wenfa Lu
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Genes
Subjects:
melatonin
apoptosis
sheep
granulosa cells
oxidative stress
Online Access:https://www.mdpi.com/2073-4425/14/5/1067

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