Transgenic mice lacking CREB and CREM in noradrenergic and serotonergic neurons respond differently to common antidepressants on tail suspension test
Abstract Evidence exists that chronic antidepressant therapy enhances CREB levels and activity. Nevertheless, the data are not conclusive, as previous analysis of transgenic mouse models has suggested that CREB inactivation in fact contributes to antidepressant-like behavior. The aim of this study w...
主要な著者: | , , , , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
Nature Portfolio
2017-10-01
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シリーズ: | Scientific Reports |
オンライン・アクセス: | https://doi.org/10.1038/s41598-017-14069-6 |