Structure-Based Design of Nipah Virus Vaccines: A Generalizable Approach to Paramyxovirus Immunogen Development

Structure-Based Design of Nipah Virus Vaccines: A Generalizable Approach to Paramyxovirus Immunogen Development

Licensed vaccines or therapeutics are rarely available for pathogens with epidemic or pandemic potential. Developing interventions for specific pathogens and defining generalizable approaches for related pathogens is a global priority and inherent to the UN Sustainable Development Goals. Nipah virus...

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Bibliographic Details
Main Authors:	Rebecca J. Loomis, Guillaume B. E. Stewart-Jones, Yaroslav Tsybovsky, Ria T. Caringal, Kaitlyn M. Morabito, Jason S. McLellan, Amy L. Chamberlain, Sean T. Nugent, Geoffrey B. Hutchinson, Lisa A. Kueltzo, John R. Mascola, Barney S. Graham
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-06-01
Series:	Frontiers in Immunology
Subjects:	Nipah virus stabilized prefusion F structure-based vaccine design G attachment protein pre-F/G chimeric immunogen pandemic preparedness
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2020.00842/full

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