A WDR35-dependent coat protein complex transports ciliary membrane cargo vesicles to cilia

A WDR35-dependent coat protein complex transports ciliary membrane cargo vesicles to cilia

Intraflagellar transport (IFT) is a highly conserved mechanism for motor-driven transport of cargo within cilia, but how this cargo is selectively transported to cilia is unclear. WDR35/IFT121 is a component of the IFT-A complex best known for its role in ciliary retrograde transport. In the absence...

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Bibliographic Details
Main Authors: Tooba Quidwai, Jiaolong Wang, Emma A Hall, Narcis A Petriman, Weihua Leng, Petra Kiesel, Jonathan N Wells, Laura C Murphy, Margaret A Keighren, Joseph A Marsh, Esben Lorentzen, Gaia Pigino, Pleasantine Mill
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-11-01
Series:eLife
Subjects:
cilia
intraflagellar transport
ciliary pocket
membrane cargos
vesicular traffic
coatomer
Online Access:https://elifesciences.org/articles/69786

Internet

https://elifesciences.org/articles/69786

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