Decreased mitochondrial DNA mutagenesis in human colorectal cancer.
Genome instability is regarded as a hallmark of cancer. Human tumors frequently carry clonally expanded mutations in their mitochondrial DNA (mtDNA), some of which may drive cancer progression and metastasis. The high prevalence of clonal mutations in tumor mtDNA has commonly led to the assumption t...
| Những tác giả chính: | , , , , , , |
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| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
| Được phát hành: |
Public Library of Science (PLoS)
2012-01-01
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| Loạt: | PLoS Genetics |
| Truy cập trực tuyến: | http://europepmc.org/articles/PMC3369930?pdf=render |