DC-SIGN Mediates the Interaction Between Neutrophils and Leishmania amazonensis-Infected Dendritic Cells to Promote DC Maturation and Parasite Elimination

DC-SIGN Mediates the Interaction Between Neutrophils and Leishmania amazonensis-Infected Dendritic Cells to Promote DC Maturation and Parasite Elimination

BackgroundLeishmaniasis is a neglected arthropod-borne disease that affects millions of people worldwide. Successful Leishmania infections require the mitigation of immune cell functions leading to parasite survival and proliferation. A large body of evidence highlights the involvement of neutrophil...

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Bibliographic Details
Main Authors: Rafael Tiburcio, Léon Dimitri Melo, Sara Nunes, Ana Luísa Augusto Barbosa, Elaine Carvalho de Oliveira, Martha Suarez, Valéria M. Borges, Natalia Tavares, Claudia Ida Brodskyn
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
leishmaniasis
polymorphonuclear cells
monocyte-derived dendritic cells
DC-SIGN
DC maturation markers
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.750648/full

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