Case report: Highly differentiated endometrial adenocarcinoma that collided with uterine cervical carcinosarcoma
Uterine collision tumor is a rare pathological type composed of two or more malignant tumors. The components of these malignant tumors do not have histological mixing and are separated by the normal mesenchyme. Collision cancer is very rare, with uterine collision tumors being even rarer. Only a few...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-01-01
|
| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1044196/full |
| _version_ | 1797942689357889536 |
|---|---|
| author | Xue Fan Xue Fan Haoyue Hu Yang Liu Songtao Tan Meng Xie Fang Zhang |
| author_facet | Xue Fan Xue Fan Haoyue Hu Yang Liu Songtao Tan Meng Xie Fang Zhang |
| author_sort | Xue Fan |
| collection | DOAJ |
| description | Uterine collision tumor is a rare pathological type composed of two or more malignant tumors. The components of these malignant tumors do not have histological mixing and are separated by the normal mesenchyme. Collision cancer is very rare, with uterine collision tumors being even rarer. Only a few cases have been reported in relation to uterine collision tumors. At present, there is no standard treatment guideline for uterine collision tumors, and a comprehensive treatment composed of surgery, radiotherapy, and chemotherapy is suggested. In this study, we report a 54-year-old female patient diagnosed with highly differentiated endometrial adenocarcinoma with cervical carcinosarcoma. The endometrial adenocarcinoma component invaded the deep myometrium (> 1/2 layer), involving the cervical glands and interstitium. The regional lymph node metastasis from endometrial adenocarcinoma was also detected. The patient underwent “transabdominal tumor cytoreduction (total hysterectomy + right adnexal resection + greater omentectomy + pelvic lymph node dissection + para-aortic lymph node dissection) + pelvic adhesion release.” In addition, she has completed adjuvant radiotherapy and chemotherapy. After reviewing previous reports of collision tumors in different positions of the uterus, we found that collision tumors between the cervix and uterine body are very uncommon. In addition, we have not found any reports on the metastasis of sarcoid components, no matter what the composition is. |
| first_indexed | 2024-04-10T20:11:29Z |
| format | Article |
| id | doaj.art-a1c74d61e88d42d4ba64480dc4df4e8e |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-10T20:11:29Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-a1c74d61e88d42d4ba64480dc4df4e8e2023-01-26T10:55:21ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-01-011010.3389/fmed.2023.10441961044196Case report: Highly differentiated endometrial adenocarcinoma that collided with uterine cervical carcinosarcomaXue Fan0Xue Fan1Haoyue Hu2Yang Liu3Songtao Tan4Meng Xie5Fang Zhang6Institute of Lung Cancer, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, ChinaSichuan Cancer Center, Sichuan Cancer Hospital and Institute, Medicine School of University of Electronic Science and Technology, Chengdu, ChinaDepartment of Medical Oncology, Sichuan Cancer Center, Sichuan Cancer Hospital and Institute, Medicine School of University of Electronic Science and Technology, Chengdu, ChinaDepartment of Pathology, Sichuan Cancer Center, Sichuan Cancer Hospital and Institute, Medicine School of University of Electronic Science and Technology, Chengdu, ChinaWest China School of Medicine, Sichuan University, Chengdu, ChinaDepartment of Pharmacy, Southwest Medical University, Luzhou, ChinaDepartment of Pathology, Sichuan Cancer Center, Sichuan Cancer Hospital and Institute, Medicine School of University of Electronic Science and Technology, Chengdu, ChinaUterine collision tumor is a rare pathological type composed of two or more malignant tumors. The components of these malignant tumors do not have histological mixing and are separated by the normal mesenchyme. Collision cancer is very rare, with uterine collision tumors being even rarer. Only a few cases have been reported in relation to uterine collision tumors. At present, there is no standard treatment guideline for uterine collision tumors, and a comprehensive treatment composed of surgery, radiotherapy, and chemotherapy is suggested. In this study, we report a 54-year-old female patient diagnosed with highly differentiated endometrial adenocarcinoma with cervical carcinosarcoma. The endometrial adenocarcinoma component invaded the deep myometrium (> 1/2 layer), involving the cervical glands and interstitium. The regional lymph node metastasis from endometrial adenocarcinoma was also detected. The patient underwent “transabdominal tumor cytoreduction (total hysterectomy + right adnexal resection + greater omentectomy + pelvic lymph node dissection + para-aortic lymph node dissection) + pelvic adhesion release.” In addition, she has completed adjuvant radiotherapy and chemotherapy. After reviewing previous reports of collision tumors in different positions of the uterus, we found that collision tumors between the cervix and uterine body are very uncommon. In addition, we have not found any reports on the metastasis of sarcoid components, no matter what the composition is.https://www.frontiersin.org/articles/10.3389/fmed.2023.1044196/fullcollision tumorendometrial adenocarcinomatherapycervical carcinosarcomapathology |
| spellingShingle | Xue Fan Xue Fan Haoyue Hu Yang Liu Songtao Tan Meng Xie Fang Zhang Case report: Highly differentiated endometrial adenocarcinoma that collided with uterine cervical carcinosarcoma Frontiers in Medicine collision tumor endometrial adenocarcinoma therapy cervical carcinosarcoma pathology |
| title | Case report: Highly differentiated endometrial adenocarcinoma that collided with uterine cervical carcinosarcoma |
| title_full | Case report: Highly differentiated endometrial adenocarcinoma that collided with uterine cervical carcinosarcoma |
| title_fullStr | Case report: Highly differentiated endometrial adenocarcinoma that collided with uterine cervical carcinosarcoma |
| title_full_unstemmed | Case report: Highly differentiated endometrial adenocarcinoma that collided with uterine cervical carcinosarcoma |
| title_short | Case report: Highly differentiated endometrial adenocarcinoma that collided with uterine cervical carcinosarcoma |
| title_sort | case report highly differentiated endometrial adenocarcinoma that collided with uterine cervical carcinosarcoma |
| topic | collision tumor endometrial adenocarcinoma therapy cervical carcinosarcoma pathology |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1044196/full |
| work_keys_str_mv | AT xuefan casereporthighlydifferentiatedendometrialadenocarcinomathatcollidedwithuterinecervicalcarcinosarcoma AT xuefan casereporthighlydifferentiatedendometrialadenocarcinomathatcollidedwithuterinecervicalcarcinosarcoma AT haoyuehu casereporthighlydifferentiatedendometrialadenocarcinomathatcollidedwithuterinecervicalcarcinosarcoma AT yangliu casereporthighlydifferentiatedendometrialadenocarcinomathatcollidedwithuterinecervicalcarcinosarcoma AT songtaotan casereporthighlydifferentiatedendometrialadenocarcinomathatcollidedwithuterinecervicalcarcinosarcoma AT mengxie casereporthighlydifferentiatedendometrialadenocarcinomathatcollidedwithuterinecervicalcarcinosarcoma AT fangzhang casereporthighlydifferentiatedendometrialadenocarcinomathatcollidedwithuterinecervicalcarcinosarcoma |