New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B

The subject of the study was phenotypic marking of the antibiotic susceptibility and MLSB resistance mechanism in Corynebacterium spp. isolated from human skin (18 isolates) and from clinical materials (19 isolates). The strains were tested for the presence of the erm(A), erm(B), erm(C), erm(X), lnu...

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Main Authors: MAGDALENA SZEMRAJ, ANNA KWASZEWSKA, ELIGIA M. SZEWCZYK
Format: Article
Language:English
Published: Sciendo 2018-06-01
Series:Polish Journal of Microbiology
Subjects:
Online Access:https://www.exeley.com/exeley/journals/polish_journal_of_microbiology/67/2/pdf/10.21307_pjm-2018-028.pdf
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author MAGDALENA SZEMRAJ
ANNA KWASZEWSKA
ELIGIA M. SZEWCZYK
author_facet MAGDALENA SZEMRAJ
ANNA KWASZEWSKA
ELIGIA M. SZEWCZYK
author_sort MAGDALENA SZEMRAJ
collection DOAJ
description The subject of the study was phenotypic marking of the antibiotic susceptibility and MLSB resistance mechanism in Corynebacterium spp. isolated from human skin (18 isolates) and from clinical materials (19 isolates). The strains were tested for the presence of the erm(A), erm(B), erm(C), erm(X), lnu(A), msr(A), msr(B) and mph(C) genes. Clinical isolates showed wide resistance to antibiotics. In 89% clinical isolates and 72% skin microbiota a constitutive type of MLSB resistance was found. In 12 clinical isolates the erm(C) gene was detected-eight of which had erm(X) as well as erm(C), two harboured erm(X), erm(C) and erm(A) and two demonstrated only erm(C).
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spelling doaj.art-a1c7c1c52c234edaa9c49d306c3ceeee2022-12-22T00:53:26ZengSciendoPolish Journal of Microbiology1733-13312544-46462018-06-0167210.21307/pjm-2018-028New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin BMAGDALENA SZEMRAJ0ANNA KWASZEWSKA1ELIGIA M. SZEWCZYK2Department of Pharmaceutical Microbiology and Microbiological Diagnostics, Medical University of Łódź,Łódź,PolandInstitute of Health Sciences, State College of Applied Sciences in Skierniewice,Skierniewice,PolandDepartment of Pharmaceutical Microbiology and Microbiological Diagnostics, Medical University of Łódź,Łódź,PolandThe subject of the study was phenotypic marking of the antibiotic susceptibility and MLSB resistance mechanism in Corynebacterium spp. isolated from human skin (18 isolates) and from clinical materials (19 isolates). The strains were tested for the presence of the erm(A), erm(B), erm(C), erm(X), lnu(A), msr(A), msr(B) and mph(C) genes. Clinical isolates showed wide resistance to antibiotics. In 89% clinical isolates and 72% skin microbiota a constitutive type of MLSB resistance was found. In 12 clinical isolates the erm(C) gene was detected-eight of which had erm(X) as well as erm(C), two harboured erm(X), erm(C) and erm(A) and two demonstrated only erm(C).https://www.exeley.com/exeley/journals/polish_journal_of_microbiology/67/2/pdf/10.21307_pjm-2018-028.pdfCorynebacterium spp.erm(C)MLS<sub>B</sub>resistance genes
spellingShingle MAGDALENA SZEMRAJ
ANNA KWASZEWSKA
ELIGIA M. SZEWCZYK
New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B
Polish Journal of Microbiology
Corynebacterium spp.
erm(C)
MLS<sub>B</sub>
resistance genes
title New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B
title_full New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B
title_fullStr New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B
title_full_unstemmed New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B
title_short New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B
title_sort new gene responsible for resistance of clinical corynebacteria to macrolide lincosamide and streptogramin b
topic Corynebacterium spp.
erm(C)
MLS<sub>B</sub>
resistance genes
url https://www.exeley.com/exeley/journals/polish_journal_of_microbiology/67/2/pdf/10.21307_pjm-2018-028.pdf
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AT annakwaszewska newgeneresponsibleforresistanceofclinicalcorynebacteriatomacrolidelincosamideandstreptograminb
AT eligiamszewczyk newgeneresponsibleforresistanceofclinicalcorynebacteriatomacrolidelincosamideandstreptograminb