New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B
The subject of the study was phenotypic marking of the antibiotic susceptibility and MLSB resistance mechanism in Corynebacterium spp. isolated from human skin (18 isolates) and from clinical materials (19 isolates). The strains were tested for the presence of the erm(A), erm(B), erm(C), erm(X), lnu...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Sciendo
2018-06-01
|
Series: | Polish Journal of Microbiology |
Subjects: | |
Online Access: | https://www.exeley.com/exeley/journals/polish_journal_of_microbiology/67/2/pdf/10.21307_pjm-2018-028.pdf |
_version_ | 1818173192671330304 |
---|---|
author | MAGDALENA SZEMRAJ ANNA KWASZEWSKA ELIGIA M. SZEWCZYK |
author_facet | MAGDALENA SZEMRAJ ANNA KWASZEWSKA ELIGIA M. SZEWCZYK |
author_sort | MAGDALENA SZEMRAJ |
collection | DOAJ |
description | The subject of the study was phenotypic marking of the antibiotic susceptibility and MLSB resistance mechanism in Corynebacterium spp. isolated from human skin (18 isolates) and from clinical materials (19 isolates). The strains were tested for the presence of the erm(A), erm(B), erm(C), erm(X), lnu(A), msr(A), msr(B) and mph(C) genes. Clinical isolates showed wide resistance to antibiotics. In 89% clinical isolates and 72% skin microbiota a constitutive type of MLSB resistance was found. In 12 clinical isolates the erm(C) gene was detected-eight of which had erm(X) as well as erm(C), two harboured erm(X), erm(C) and erm(A) and two demonstrated only erm(C). |
first_indexed | 2024-12-11T19:24:36Z |
format | Article |
id | doaj.art-a1c7c1c52c234edaa9c49d306c3ceeee |
institution | Directory Open Access Journal |
issn | 1733-1331 2544-4646 |
language | English |
last_indexed | 2024-12-11T19:24:36Z |
publishDate | 2018-06-01 |
publisher | Sciendo |
record_format | Article |
series | Polish Journal of Microbiology |
spelling | doaj.art-a1c7c1c52c234edaa9c49d306c3ceeee2022-12-22T00:53:26ZengSciendoPolish Journal of Microbiology1733-13312544-46462018-06-0167210.21307/pjm-2018-028New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin BMAGDALENA SZEMRAJ0ANNA KWASZEWSKA1ELIGIA M. SZEWCZYK2Department of Pharmaceutical Microbiology and Microbiological Diagnostics, Medical University of Łódź,Łódź,PolandInstitute of Health Sciences, State College of Applied Sciences in Skierniewice,Skierniewice,PolandDepartment of Pharmaceutical Microbiology and Microbiological Diagnostics, Medical University of Łódź,Łódź,PolandThe subject of the study was phenotypic marking of the antibiotic susceptibility and MLSB resistance mechanism in Corynebacterium spp. isolated from human skin (18 isolates) and from clinical materials (19 isolates). The strains were tested for the presence of the erm(A), erm(B), erm(C), erm(X), lnu(A), msr(A), msr(B) and mph(C) genes. Clinical isolates showed wide resistance to antibiotics. In 89% clinical isolates and 72% skin microbiota a constitutive type of MLSB resistance was found. In 12 clinical isolates the erm(C) gene was detected-eight of which had erm(X) as well as erm(C), two harboured erm(X), erm(C) and erm(A) and two demonstrated only erm(C).https://www.exeley.com/exeley/journals/polish_journal_of_microbiology/67/2/pdf/10.21307_pjm-2018-028.pdfCorynebacterium spp.erm(C)MLS<sub>B</sub>resistance genes |
spellingShingle | MAGDALENA SZEMRAJ ANNA KWASZEWSKA ELIGIA M. SZEWCZYK New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B Polish Journal of Microbiology Corynebacterium spp. erm(C) MLS<sub>B</sub> resistance genes |
title | New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B |
title_full | New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B |
title_fullStr | New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B |
title_full_unstemmed | New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B |
title_short | New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B |
title_sort | new gene responsible for resistance of clinical corynebacteria to macrolide lincosamide and streptogramin b |
topic | Corynebacterium spp. erm(C) MLS<sub>B</sub> resistance genes |
url | https://www.exeley.com/exeley/journals/polish_journal_of_microbiology/67/2/pdf/10.21307_pjm-2018-028.pdf |
work_keys_str_mv | AT magdalenaszemraj newgeneresponsibleforresistanceofclinicalcorynebacteriatomacrolidelincosamideandstreptograminb AT annakwaszewska newgeneresponsibleforresistanceofclinicalcorynebacteriatomacrolidelincosamideandstreptograminb AT eligiamszewczyk newgeneresponsibleforresistanceofclinicalcorynebacteriatomacrolidelincosamideandstreptograminb |