Multicomponent Materials to Improve Solubility: Eutectics of Drug Aminoglutethimide

Multicomponent Materials to Improve Solubility: Eutectics of Drug Aminoglutethimide

Here, we report the synthesis and experimental characterization of three drug-drug eutectic mixtures of drug aminoglutethimide (AMG) with caffeine (CAF), nicotinamide (NIC) and ethenzamide (ZMD). The eutectic mixtures i.e., AMG-CAF (1:0.4, molar ratio), AMG-NIC (1:1.9, molar ratio) and AMG-ZMD (1:1....

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Bibliographic Details
Main Authors: Basanta Saikia, Andreas Seidel-Morgenstern, Heike Lorenz
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Crystals
Subjects:
aminoglutethimide
eutectic mixture
solubility
melt phase diagram
Online Access:https://www.mdpi.com/2073-4352/12/1/40

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