Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives
Abstract Here I review the scientific background, current stage of development and future perspectives that I foresee in the field of genetic manipulation of hematopoietic stem cells with a special emphasis on clinical applications.
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| Format: | Article |
| Language: | English |
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Springer Nature
2019-03-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.201809958 |
| _version_ | 1797284032591953920 |
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| author | Luigi Naldini |
| author_facet | Luigi Naldini |
| author_sort | Luigi Naldini |
| collection | DOAJ |
| description | Abstract Here I review the scientific background, current stage of development and future perspectives that I foresee in the field of genetic manipulation of hematopoietic stem cells with a special emphasis on clinical applications. |
| first_indexed | 2024-03-07T17:43:07Z |
| format | Article |
| id | doaj.art-a1cab8539bed46658774aadd2eff155b |
| institution | Directory Open Access Journal |
| issn | 1757-4676 1757-4684 |
| language | English |
| last_indexed | 2024-03-07T17:43:07Z |
| publishDate | 2019-03-01 |
| publisher | Springer Nature |
| record_format | Article |
| series | EMBO Molecular Medicine |
| spelling | doaj.art-a1cab8539bed46658774aadd2eff155b2024-03-02T15:56:46ZengSpringer NatureEMBO Molecular Medicine1757-46761757-46842019-03-01113n/an/a10.15252/emmm.201809958Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectivesLuigi Naldini0San Raffaele Telethon Institute for Gene Therapy IRCCS San Raffaele Hospital and Research Institute “Vita ‐ Salute San Raffaele” University Medical School Milan ItalyAbstract Here I review the scientific background, current stage of development and future perspectives that I foresee in the field of genetic manipulation of hematopoietic stem cells with a special emphasis on clinical applications.https://doi.org/10.15252/emmm.201809958gene editinggene therapyhematopoietic stem cellslentiviral vectorstransplantation |
| spellingShingle | Luigi Naldini Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives EMBO Molecular Medicine gene editing gene therapy hematopoietic stem cells lentiviral vectors transplantation |
| title | Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives |
| title_full | Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives |
| title_fullStr | Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives |
| title_full_unstemmed | Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives |
| title_short | Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives |
| title_sort | genetic engineering of hematopoiesis current stage of clinical translation and future perspectives |
| topic | gene editing gene therapy hematopoietic stem cells lentiviral vectors transplantation |
| url | https://doi.org/10.15252/emmm.201809958 |
| work_keys_str_mv | AT luiginaldini geneticengineeringofhematopoiesiscurrentstageofclinicaltranslationandfutureperspectives |