The Influence of Loading Program on the Stimulated Callus Mineralization
The aim of this work is to describe the change of physical properties of the callus material with the use of the proposed mathematical model for callus remodeling. Callus tissue can be considered as a biomaterial where it’s properties change over time due to the stimulated healing process....
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-10-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/9/20/4268 |
| _version_ | 1818031435263508480 |
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| author | Justyna Miodowska Jan Bielski |
| author_facet | Justyna Miodowska Jan Bielski |
| author_sort | Justyna Miodowska |
| collection | DOAJ |
| description | The aim of this work is to describe the change of physical properties of the callus material with the use of the proposed mathematical model for callus remodeling. Callus tissue can be considered as a biomaterial where it’s properties change over time due to the stimulated healing process. The proposed model is based on the mechanical stimulus theory. It is used to estimate the stress-stimulated change in the callus, Young’s modulus, and the density in the case of a mandible fracture. Three healing loading programs are discussed and compared: optimal, intermittent, and intermittent with residual load. Here, the optimal loading program is understood as the in-time change of stimulating loads, which results in the shortest necessary healing time and, simultaneously, in the most uniform distribution of material density in the analyzed domain. The necessary healing time is a period after which the callus density (and hence the Young’s modulus) reaches the desired value. The results of the study suggest a significant difference in the value of the callus maximal density between all three analyzed loading programs for a given healing time interval. The highest values of the density are obtained using the optimal loading program, however, all three programs provide satisfactory density distributions. The analytical results are compared with the callus density estimation based on the computer tomography (CT) medical data. |
| first_indexed | 2024-12-10T05:51:26Z |
| format | Article |
| id | doaj.art-a1cf57ea960e4f93962244692e4125c0 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-12-10T05:51:26Z |
| publishDate | 2019-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-a1cf57ea960e4f93962244692e4125c02022-12-22T02:00:02ZengMDPI AGApplied Sciences2076-34172019-10-01920426810.3390/app9204268app9204268The Influence of Loading Program on the Stimulated Callus MineralizationJustyna Miodowska0Jan Bielski1Institute of Applied Mechanics, Cracow University of Technology, al. Jana Pawła II 37, 31-864 Cracow, PolandInstitute of Applied Mechanics, Cracow University of Technology, al. Jana Pawła II 37, 31-864 Cracow, PolandThe aim of this work is to describe the change of physical properties of the callus material with the use of the proposed mathematical model for callus remodeling. Callus tissue can be considered as a biomaterial where it’s properties change over time due to the stimulated healing process. The proposed model is based on the mechanical stimulus theory. It is used to estimate the stress-stimulated change in the callus, Young’s modulus, and the density in the case of a mandible fracture. Three healing loading programs are discussed and compared: optimal, intermittent, and intermittent with residual load. Here, the optimal loading program is understood as the in-time change of stimulating loads, which results in the shortest necessary healing time and, simultaneously, in the most uniform distribution of material density in the analyzed domain. The necessary healing time is a period after which the callus density (and hence the Young’s modulus) reaches the desired value. The results of the study suggest a significant difference in the value of the callus maximal density between all three analyzed loading programs for a given healing time interval. The highest values of the density are obtained using the optimal loading program, however, all three programs provide satisfactory density distributions. The analytical results are compared with the callus density estimation based on the computer tomography (CT) medical data.https://www.mdpi.com/2076-3417/9/20/4268callus remodelingfracturetissue healingoptimal loading |
| spellingShingle | Justyna Miodowska Jan Bielski The Influence of Loading Program on the Stimulated Callus Mineralization Applied Sciences callus remodeling fracture tissue healing optimal loading |
| title | The Influence of Loading Program on the Stimulated Callus Mineralization |
| title_full | The Influence of Loading Program on the Stimulated Callus Mineralization |
| title_fullStr | The Influence of Loading Program on the Stimulated Callus Mineralization |
| title_full_unstemmed | The Influence of Loading Program on the Stimulated Callus Mineralization |
| title_short | The Influence of Loading Program on the Stimulated Callus Mineralization |
| title_sort | influence of loading program on the stimulated callus mineralization |
| topic | callus remodeling fracture tissue healing optimal loading |
| url | https://www.mdpi.com/2076-3417/9/20/4268 |
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