A study of occurrence and risk factors of age-related macular degeneration in a region of Central India

Purpose: The purpose of the study is to determine the occurrence of age-related macular degeneration (AMD) in patients aged >50 years and to study risk factors associated with it. Materials and Methods: It was a cross-sectional prospective study, in which 907 patients aged 50 years and above of b...

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Main Authors: Archana Sunil Nikose, Arpita Sthapak, Mayuri Patil
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Journal of Clinical Ophthalmology and Research
Subjects:
Online Access:http://www.jcor.in/article.asp?issn=2320-3897;year=2019;volume=7;issue=3;spage=97;epage=100;aulast=Nikose
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author Archana Sunil Nikose
Arpita Sthapak
Mayuri Patil
author_facet Archana Sunil Nikose
Arpita Sthapak
Mayuri Patil
author_sort Archana Sunil Nikose
collection DOAJ
description Purpose: The purpose of the study is to determine the occurrence of age-related macular degeneration (AMD) in patients aged >50 years and to study risk factors associated with it. Materials and Methods: It was a cross-sectional prospective study, in which 907 patients aged 50 years and above of both sexes were studied who visited eye outpatient department of our tertiary hospital between October 2014 and September 2016. Visual acuity, slit-lamp examination, and disc and macular evaluation with 90D lens and 20D using indirect ophthalmoscope were performed. AMD was confirmed by doing fundus fluorescein angiography. Association of AMD with hypertension, diabetes, cardiovascular disease, smoking, alcohol consumption, and body mass index were studied. Results: Out of 907 patients, 21 had AMD, i.e., the occurrence was 2.3%. Of 21 patients, 15 had early AMD (1.6%) and 6 had late AMD (0.7%). The highest occurrence of 9.75% was seen in age group of 80 years and above, whereas other risk factors of AMD, i.e., smoking showed P = 0.1261, cardiovascular disease P = 0.0251, and prior cataract surgery with P = 0.0001. Conclusion: Age was found to be strong and consistent risk factor of AMD. Smoking, cardiovascular disease, and prior cataract surgery were significantly associated with AMD.
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spelling doaj.art-a1d161da338149378b5c7f467d34d2392022-12-22T02:24:41ZengWolters Kluwer Medknow PublicationsJournal of Clinical Ophthalmology and Research2320-38972019-01-01739710010.4103/jcor.jcor_87_17A study of occurrence and risk factors of age-related macular degeneration in a region of Central IndiaArchana Sunil NikoseArpita SthapakMayuri PatilPurpose: The purpose of the study is to determine the occurrence of age-related macular degeneration (AMD) in patients aged >50 years and to study risk factors associated with it. Materials and Methods: It was a cross-sectional prospective study, in which 907 patients aged 50 years and above of both sexes were studied who visited eye outpatient department of our tertiary hospital between October 2014 and September 2016. Visual acuity, slit-lamp examination, and disc and macular evaluation with 90D lens and 20D using indirect ophthalmoscope were performed. AMD was confirmed by doing fundus fluorescein angiography. Association of AMD with hypertension, diabetes, cardiovascular disease, smoking, alcohol consumption, and body mass index were studied. Results: Out of 907 patients, 21 had AMD, i.e., the occurrence was 2.3%. Of 21 patients, 15 had early AMD (1.6%) and 6 had late AMD (0.7%). The highest occurrence of 9.75% was seen in age group of 80 years and above, whereas other risk factors of AMD, i.e., smoking showed P = 0.1261, cardiovascular disease P = 0.0251, and prior cataract surgery with P = 0.0001. Conclusion: Age was found to be strong and consistent risk factor of AMD. Smoking, cardiovascular disease, and prior cataract surgery were significantly associated with AMD.http://www.jcor.in/article.asp?issn=2320-3897;year=2019;volume=7;issue=3;spage=97;epage=100;aulast=Nikoseage-related macular degenerationdrusenfundus fluorescein angiographyoptical coherence tomography
spellingShingle Archana Sunil Nikose
Arpita Sthapak
Mayuri Patil
A study of occurrence and risk factors of age-related macular degeneration in a region of Central India
Journal of Clinical Ophthalmology and Research
age-related macular degeneration
drusen
fundus fluorescein angiography
optical coherence tomography
title A study of occurrence and risk factors of age-related macular degeneration in a region of Central India
title_full A study of occurrence and risk factors of age-related macular degeneration in a region of Central India
title_fullStr A study of occurrence and risk factors of age-related macular degeneration in a region of Central India
title_full_unstemmed A study of occurrence and risk factors of age-related macular degeneration in a region of Central India
title_short A study of occurrence and risk factors of age-related macular degeneration in a region of Central India
title_sort study of occurrence and risk factors of age related macular degeneration in a region of central india
topic age-related macular degeneration
drusen
fundus fluorescein angiography
optical coherence tomography
url http://www.jcor.in/article.asp?issn=2320-3897;year=2019;volume=7;issue=3;spage=97;epage=100;aulast=Nikose
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