The TGFβ1 Promoter SNP C-509T and Food Sensitization Promote Esophageal Remodeling in Pediatric Eosinophilic Esophagitis.

The TGFβ1 Promoter SNP C-509T and Food Sensitization Promote Esophageal Remodeling in Pediatric Eosinophilic Esophagitis.

Eosinophilic esophagitis (EoE) is a chronic antigen mediated disease associated with substantial esophageal remodeling and fibrosis. The functional TGFβ1 promoter SNP C-509 associates with renal fibrosis and asthma. The effect of TGFβ1 genotype and EoE severity or potential gene-environment interact...

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Bibliographic Details
Main Authors: Renee Rawson, Arjun Anilkumar, Robert O Newbury, Vineet Bafna, Melissa Aquino, Jacob Palmquist, Hal M Hoffman, James L Mueller, Ranjan Dohil, David H Broide, Seema S Aceves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4678166?pdf=render

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http://europepmc.org/articles/PMC4678166?pdf=render

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