Pharmacological Properties of Chalcones: A Review of Preclinical Including Molecular Mechanisms and Clinical Evidence

Pharmacological Properties of Chalcones: A Review of Preclinical Including Molecular Mechanisms and Clinical Evidence

Chalcones are among the leading bioactive flavonoids with a therapeutic potential implicated to an array of bioactivities investigated by a series of preclinical and clinical studies. In this article, different scientific databases were searched to retrieve studies depicting the biological activitie...

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Bibliographic Details
Main Authors: Bahare Salehi, Cristina Quispe, Imane Chamkhi, Nasreddine El Omari, Abdelaali Balahbib, Javad Sharifi-Rad, Abdelhakim Bouyahya, Muhammad Akram, Mehwish Iqbal, Anca Oana Docea, Constantin Caruntu, Gerardo Leyva-Gómez, Abhijit Dey, Miquel Martorell, Daniela Calina, Víctor López, Francisco Les
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
chalcones
flavonoids
bioavailability
pharmacological studies
molecular mechanisms
clinical trials
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.592654/full

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