Curcumin Regulates Anti-Inflammatory Responses by JAK/STAT/SOCS Signaling Pathway in BV-2 Microglial Cells

Curcumin Regulates Anti-Inflammatory Responses by JAK/STAT/SOCS Signaling Pathway in BV-2 Microglial Cells

Microglia play important physiological roles in central nervous system (CNS) homeostasis and in the pathogenesis of inflammatory brain diseases. Inflammation stimulates microglia to secrete cytokines and chemokines that guide immune cells to sites of injury/inflammation. Neuroinflammation is also st...

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Bibliographic Details
Main Authors: Chiara Porro, Antonia Cianciulli, Teresa Trotta, Dario Domenico Lofrumento, Maria Antonietta Panaro
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Biology
Subjects:
microglia
SOCS-1
curcumin
JAK/STAT
IL-4
IL-10
Online Access:https://www.mdpi.com/2079-7737/8/3/51

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