Development of Personalized Therapeutic Strategies by Targeting Actionable Vulnerabilities in Metastatic and Chemotherapy-Resistant Breast Cancer PDXs
Human breast cancer is characterized by a high degree of inter-patients heterogeneity in terms of histology, genomic alterations, gene expression patterns, and metastatic behavior, which deeply influences individual prognosis and treatment response. The main cause of mortality in breast cancer is th...
Main Authors: | Simona Punzi, Marine Meliksetian, Laura Riva, Federica Marocchi, Giancarlo Pruneri, Carmen Criscitiello, Franco Orsi, Lorenzo Spaggiari, Monica Casiraghi, Paolo Della Vigna, Lucilla Luzi, Giuseppe Curigliano, Pier Giuseppe Pelicci, Luisa Lanfrancone |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-06-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/8/6/605 |
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