Prostate Cancer Diagnosis, Treatment and Outcomes in Patients with Previous or Synchronous Colorectal Cancer: A Systematic Review of Published Evidence
The management of patients with prostate cancer (PCa) and previous or synchronous colorectal cancer (CRC) represents a challenging issue. A systematic review was performed in May 2022 to summarize available evidence about the diagnosis, management, and outcomes of these patients. Twenty-seven studie...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Diagnostics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4418/12/6/1475 |
| _version_ | 1827660943289483264 |
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| author | Giuseppe Celentano Massimiliano Creta Luigi Napolitano Marco Abate Roberto La Rocca Marco Capece Claudia Mirone Simone Morra Francesco Di Bello Luigi Cirillo Francesco Mangiapia Gianluigi Califano Claudia Collà Ruvolo Caterina Sagnelli Antonello Sica Armando Calogero Fabrizio Iacono Ferdinando Fusco Vincenzo Mirone Nicola Longo |
| author_facet | Giuseppe Celentano Massimiliano Creta Luigi Napolitano Marco Abate Roberto La Rocca Marco Capece Claudia Mirone Simone Morra Francesco Di Bello Luigi Cirillo Francesco Mangiapia Gianluigi Califano Claudia Collà Ruvolo Caterina Sagnelli Antonello Sica Armando Calogero Fabrizio Iacono Ferdinando Fusco Vincenzo Mirone Nicola Longo |
| author_sort | Giuseppe Celentano |
| collection | DOAJ |
| description | The management of patients with prostate cancer (PCa) and previous or synchronous colorectal cancer (CRC) represents a challenging issue. A systematic review was performed in May 2022 to summarize available evidence about the diagnosis, management, and outcomes of these patients. Twenty-seven studies involving 252 patients were identified. Overall, 163 (64.7%) and 89 (35.3%) patients had synchronous and metachronous PCa and CRC, respectively. In patients with synchronous diseases, PCa treatment involved active surveillance in 1 patient, radical prostatectomy (RP) in 36 patients, radiotherapy (RT) in 60 patients, RP plus RT in 1 patient, proton beam therapy in 1 patient, and cryoablation in 1 patient. In patients with previous CRC treatment, prostate biopsy was mostly performed by transrectal approach (<i>n =</i> 24). The trans-perineal and suprapubic approaches were adopted in 12 and 6 cases, respectively. Surgical PCa treatment in these cases involved endoscopic extraperitoneal RP, robot-assisted RP, and not otherwise specified RP in 30, 15, and 2 cases, respectively. Biochemical recurrence rates ranged from 20% to 28%. Non-surgical PCa treatment options included brachytherapy, RT plus androgen deprivation therapy, and RT alone in 23, 2 and 4 patients, respectively. PCa specific survival was reported by one study and was 100%. |
| first_indexed | 2024-03-09T23:59:32Z |
| format | Article |
| id | doaj.art-a1d8aa17b6244cd5a14ea8c79b3fa71c |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T23:59:32Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-a1d8aa17b6244cd5a14ea8c79b3fa71c2023-11-23T16:18:46ZengMDPI AGDiagnostics2075-44182022-06-01126147510.3390/diagnostics12061475Prostate Cancer Diagnosis, Treatment and Outcomes in Patients with Previous or Synchronous Colorectal Cancer: A Systematic Review of Published EvidenceGiuseppe Celentano0Massimiliano Creta1Luigi Napolitano2Marco Abate3Roberto La Rocca4Marco Capece5Claudia Mirone6Simone Morra7Francesco Di Bello8Luigi Cirillo9Francesco Mangiapia10Gianluigi Califano11Claudia Collà Ruvolo12Caterina Sagnelli13Antonello Sica14Armando Calogero15Fabrizio Iacono16Ferdinando Fusco17Vincenzo Mirone18Nicola Longo19Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyMultidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania “Luigi Vanvitelli”, 80123 Naples, ItalyDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyDepartment of Mental Health and Public Medicine, University of Campania “Luigi Vanvitelli”, 80131 Naples, ItalyDepartment of Precision Medicine, University of Campania “Luigi Vanvitelli”, 80123 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80130 Naples, ItalyDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyUrology Unit, Department of Woman, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, 80131 Naples, ItalyDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, ItalyThe management of patients with prostate cancer (PCa) and previous or synchronous colorectal cancer (CRC) represents a challenging issue. A systematic review was performed in May 2022 to summarize available evidence about the diagnosis, management, and outcomes of these patients. Twenty-seven studies involving 252 patients were identified. Overall, 163 (64.7%) and 89 (35.3%) patients had synchronous and metachronous PCa and CRC, respectively. In patients with synchronous diseases, PCa treatment involved active surveillance in 1 patient, radical prostatectomy (RP) in 36 patients, radiotherapy (RT) in 60 patients, RP plus RT in 1 patient, proton beam therapy in 1 patient, and cryoablation in 1 patient. In patients with previous CRC treatment, prostate biopsy was mostly performed by transrectal approach (<i>n =</i> 24). The trans-perineal and suprapubic approaches were adopted in 12 and 6 cases, respectively. Surgical PCa treatment in these cases involved endoscopic extraperitoneal RP, robot-assisted RP, and not otherwise specified RP in 30, 15, and 2 cases, respectively. Biochemical recurrence rates ranged from 20% to 28%. Non-surgical PCa treatment options included brachytherapy, RT plus androgen deprivation therapy, and RT alone in 23, 2 and 4 patients, respectively. PCa specific survival was reported by one study and was 100%.https://www.mdpi.com/2075-4418/12/6/1475prostate cancercolorectal cancersynchronous cancermetachronous cancer |
| spellingShingle | Giuseppe Celentano Massimiliano Creta Luigi Napolitano Marco Abate Roberto La Rocca Marco Capece Claudia Mirone Simone Morra Francesco Di Bello Luigi Cirillo Francesco Mangiapia Gianluigi Califano Claudia Collà Ruvolo Caterina Sagnelli Antonello Sica Armando Calogero Fabrizio Iacono Ferdinando Fusco Vincenzo Mirone Nicola Longo Prostate Cancer Diagnosis, Treatment and Outcomes in Patients with Previous or Synchronous Colorectal Cancer: A Systematic Review of Published Evidence Diagnostics prostate cancer colorectal cancer synchronous cancer metachronous cancer |
| title | Prostate Cancer Diagnosis, Treatment and Outcomes in Patients with Previous or Synchronous Colorectal Cancer: A Systematic Review of Published Evidence |
| title_full | Prostate Cancer Diagnosis, Treatment and Outcomes in Patients with Previous or Synchronous Colorectal Cancer: A Systematic Review of Published Evidence |
| title_fullStr | Prostate Cancer Diagnosis, Treatment and Outcomes in Patients with Previous or Synchronous Colorectal Cancer: A Systematic Review of Published Evidence |
| title_full_unstemmed | Prostate Cancer Diagnosis, Treatment and Outcomes in Patients with Previous or Synchronous Colorectal Cancer: A Systematic Review of Published Evidence |
| title_short | Prostate Cancer Diagnosis, Treatment and Outcomes in Patients with Previous or Synchronous Colorectal Cancer: A Systematic Review of Published Evidence |
| title_sort | prostate cancer diagnosis treatment and outcomes in patients with previous or synchronous colorectal cancer a systematic review of published evidence |
| topic | prostate cancer colorectal cancer synchronous cancer metachronous cancer |
| url | https://www.mdpi.com/2075-4418/12/6/1475 |
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