Antioxidant Potential of ulva rigida c. Agardh Extract: Protection from Oxidative Stress Hypothyroidism
<p>The purpose of this study was to evaluate the effects of <em>Ulva rigida</em><strong> </strong>C. Agardh, one of the green algae, on and antioxidative system in the propylthiouracil (PTU)-induced hypothyroid rats. Thirty-two rats randomly divided into four groups: co...
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| Format: | Article |
| Language: | English |
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International Journal of Secondary Metabolite
2014-06-01
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| Series: | International Journal of Secondary Metabolite |
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| Online Access: | http://ijate.net/index.php/ijsm/article/view/51 |
| _version_ | 1797913011932889088 |
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| author | S. TAŞ |
| author_facet | S. TAŞ |
| author_sort | S. TAŞ |
| collection | DOAJ |
| description | <p>The purpose of this study was to evaluate the effects of <em>Ulva rigida</em><strong> </strong>C. Agardh, one of the green algae, on and antioxidative system in the propylthiouracil (PTU)-induced hypothyroid rats. Thirty-two rats randomly divided into four groups: control (C), control+<em>U. rigida</em> extract (C+UR), hypothyroid (H) and hypothyroid+<em>U. rigida</em> extract (H+UR). <em>U. rigida</em> (2%) was administered in drinking water for 5 weeks after the induction of hypothyroidism. Hypothyroid rats were under oxidative stress as reflected by icreased plasma and tissue malondialdehyde (MDA) levels. <em>U. rigida </em>reduced serum total cholesterol and,- triglyceride levels and plasma and heart skeletal muscle, liver and,- kidney tissue MDA levels in the H+UR group. Serum total cholesterol and tissues MDA levels were reduced in the C+UR group. Whole blood glutathione peroxidase and erythrocyte superoxide dismutase activities were increased in the H+UR and C+UR groups compared with those of te respective control groups. Paraoxonase and arylesterase activities were lower in the H group and <em>U. rigida</em> increased paraoxonase and arylesterase activities in C+UR and H+UR groups. We conclude that hypothyroidism is associated with oxidative stress and, <em>U. rigida</em> extract might have a potential use as a protective antioxidant agent in hypothroidism.</p> |
| first_indexed | 2024-04-10T12:04:54Z |
| format | Article |
| id | doaj.art-a1daf4b21eec4c7196717858865839ea |
| institution | Directory Open Access Journal |
| issn | 2148-6905 |
| language | English |
| last_indexed | 2024-04-10T12:04:54Z |
| publishDate | 2014-06-01 |
| publisher | International Journal of Secondary Metabolite |
| record_format | Article |
| series | International Journal of Secondary Metabolite |
| spelling | doaj.art-a1daf4b21eec4c7196717858865839ea2023-02-15T16:16:20ZengInternational Journal of Secondary MetaboliteInternational Journal of Secondary Metabolite2148-69052014-06-0111-243Antioxidant Potential of ulva rigida c. Agardh Extract: Protection from Oxidative Stress HypothyroidismS. TAŞ0Uludag University<p>The purpose of this study was to evaluate the effects of <em>Ulva rigida</em><strong> </strong>C. Agardh, one of the green algae, on and antioxidative system in the propylthiouracil (PTU)-induced hypothyroid rats. Thirty-two rats randomly divided into four groups: control (C), control+<em>U. rigida</em> extract (C+UR), hypothyroid (H) and hypothyroid+<em>U. rigida</em> extract (H+UR). <em>U. rigida</em> (2%) was administered in drinking water for 5 weeks after the induction of hypothyroidism. Hypothyroid rats were under oxidative stress as reflected by icreased plasma and tissue malondialdehyde (MDA) levels. <em>U. rigida </em>reduced serum total cholesterol and,- triglyceride levels and plasma and heart skeletal muscle, liver and,- kidney tissue MDA levels in the H+UR group. Serum total cholesterol and tissues MDA levels were reduced in the C+UR group. Whole blood glutathione peroxidase and erythrocyte superoxide dismutase activities were increased in the H+UR and C+UR groups compared with those of te respective control groups. Paraoxonase and arylesterase activities were lower in the H group and <em>U. rigida</em> increased paraoxonase and arylesterase activities in C+UR and H+UR groups. We conclude that hypothyroidism is associated with oxidative stress and, <em>U. rigida</em> extract might have a potential use as a protective antioxidant agent in hypothroidism.</p>http://ijate.net/index.php/ijsm/article/view/51Ulva rigida, hypothyroidism, oxidative stress, antioxidant |
| spellingShingle | S. TAŞ Antioxidant Potential of ulva rigida c. Agardh Extract: Protection from Oxidative Stress Hypothyroidism International Journal of Secondary Metabolite Ulva rigida, hypothyroidism, oxidative stress, antioxidant |
| title | Antioxidant Potential of ulva rigida c. Agardh Extract: Protection from Oxidative Stress Hypothyroidism |
| title_full | Antioxidant Potential of ulva rigida c. Agardh Extract: Protection from Oxidative Stress Hypothyroidism |
| title_fullStr | Antioxidant Potential of ulva rigida c. Agardh Extract: Protection from Oxidative Stress Hypothyroidism |
| title_full_unstemmed | Antioxidant Potential of ulva rigida c. Agardh Extract: Protection from Oxidative Stress Hypothyroidism |
| title_short | Antioxidant Potential of ulva rigida c. Agardh Extract: Protection from Oxidative Stress Hypothyroidism |
| title_sort | antioxidant potential of ulva rigida c agardh extract protection from oxidative stress hypothyroidism |
| topic | Ulva rigida, hypothyroidism, oxidative stress, antioxidant |
| url | http://ijate.net/index.php/ijsm/article/view/51 |
| work_keys_str_mv | AT stas antioxidantpotentialofulvarigidacagardhextractprotectionfromoxidativestresshypothyroidism |