Protein kinase Cdelta stimulates proteasome-dependent degradation of C/EBPalpha during apoptosis induction of leukemic cells.

Protein kinase Cdelta stimulates proteasome-dependent degradation of C/EBPalpha during apoptosis induction of leukemic cells.

BACKGROUND:The precise regulation and maintenance of balance between cell proliferation, differentiation and death in metazoan are critical for tissue homeostasis. CCAAT/enhancer-binding protein alpha (C/EBPalpha) has been implicated as a key regulator of differentiation and proliferation in various...

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Bibliographic Details
Main Authors: Meng Zhao, Xu-Fang Duan, Xu-Yun Zhao, Bo Zhang, Ying Lu, Wei Liu, Jin-Ke Cheng, Guo-Qiang Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2719015?pdf=render

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