Base metal-catalyzed benzylic oxidation of (aryl)(heteroaryl)methanes with molecular oxygen

Base metal-catalyzed benzylic oxidation of (aryl)(heteroaryl)methanes with molecular oxygen

The methylene group of various substituted 2- and 4-benzylpyridines, benzyldiazines and benzyl(iso)quinolines was successfully oxidized to the corresponding benzylic ketones using a copper or iron catalyst and molecular oxygen as the stoichiometric oxidant. Application of the protocol in API synthes...

Full description

Bibliographic Details
Main Authors: Hans Sterckx, Johan De Houwer, Carl Mensch, Wouter Herrebout, Kourosch Abbaspour Tehrani, Bert U. W. Maes
Format: Article
Language:English
Published: Beilstein-Institut 2016-01-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
base metal
benzylic
catalyzed
molecular oxygen
oxygenation
Online Access:https://doi.org/10.3762/bjoc.12.16

Internet

https://doi.org/10.3762/bjoc.12.16

Similar Items