Nutritional Treatment of Hypertriglyceridemia in Childhood: From Healthy-Heart Counselling to Life-Saving Diet

Hypertriglyceridemia is a lipid disorder with a varying prevalence; it is very common if we consider triglyceride plasma values slightly above the threshold, whereas it is extremely rare if only severely elevated triglyceride levels are considered. In most cases, severe forms of hypertriglyceridemia...

Full description

Bibliographic Details
Main Authors: Maria Elena Capra, Giacomo Biasucci, Giuseppe Banderali, Cristina Pederiva
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/15/5/1088
_version_ 1797614678142091264
author Maria Elena Capra
Giacomo Biasucci
Giuseppe Banderali
Cristina Pederiva
author_facet Maria Elena Capra
Giacomo Biasucci
Giuseppe Banderali
Cristina Pederiva
author_sort Maria Elena Capra
collection DOAJ
description Hypertriglyceridemia is a lipid disorder with a varying prevalence; it is very common if we consider triglyceride plasma values slightly above the threshold, whereas it is extremely rare if only severely elevated triglyceride levels are considered. In most cases, severe forms of hypertriglyceridemia are caused by genetic mutations in the genes that regulate triglyceride metabolism, thus leading to extreme triglyceride plasma values and acute pancreatitis risk. Secondary forms of hypertriglyceridemia are usually less severe and are mainly associated with weight excess, but they can also be linked to liver, kidney, endocrinologic, or autoimmune diseases or to some class of drugs. Nutritional intervention is the milestone treatment for patients with hypertriglyceridemia and it has to be modulated on the underlying cause and on triglyceride plasma levels. In pediatric patients, nutritional intervention must be tailored according to specific age-related energy, growth and neurodevelopment requests. Nutritional intervention is extremely strict in case of severe hypertriglyceridemia, whereas it is similar to good healthy nutritional habits counselling for mild forms, mainly related to wrong habits and lifestyles, and to secondary causes. The aim of this narrative review is to define different nutritional intervention for various forms of hypertriglyceridemia in children and adolescents.
first_indexed 2024-03-11T07:15:44Z
format Article
id doaj.art-a1e050019b2f447cb136efe0e1dc1137
institution Directory Open Access Journal
issn 2072-6643
language English
last_indexed 2024-03-11T07:15:44Z
publishDate 2023-02-01
publisher MDPI AG
record_format Article
series Nutrients
spelling doaj.art-a1e050019b2f447cb136efe0e1dc11372023-11-17T08:19:25ZengMDPI AGNutrients2072-66432023-02-01155108810.3390/nu15051088Nutritional Treatment of Hypertriglyceridemia in Childhood: From Healthy-Heart Counselling to Life-Saving DietMaria Elena Capra0Giacomo Biasucci1Giuseppe Banderali2Cristina Pederiva3Centre for Pediatric Dyslipidemias, Pediatrics and Neonatology Unit, University of Parma, Guglielmo da Saliceto Hospital, 29121 Piacenza, ItalyCentre for Pediatric Dyslipidemias, Pediatrics and Neonatology Unit, University of Parma, Guglielmo da Saliceto Hospital, 29121 Piacenza, ItalyClinical Service for Dyslipidemias, Study and Prevention of Atherosclerosis in Childhood, Pediatrics Unit, ASST-Santi Paolo e Carlo, 20142 Milan, ItalySocietà Italiana di Nutrizione Pediatrica, 20126 Milan, ItalyHypertriglyceridemia is a lipid disorder with a varying prevalence; it is very common if we consider triglyceride plasma values slightly above the threshold, whereas it is extremely rare if only severely elevated triglyceride levels are considered. In most cases, severe forms of hypertriglyceridemia are caused by genetic mutations in the genes that regulate triglyceride metabolism, thus leading to extreme triglyceride plasma values and acute pancreatitis risk. Secondary forms of hypertriglyceridemia are usually less severe and are mainly associated with weight excess, but they can also be linked to liver, kidney, endocrinologic, or autoimmune diseases or to some class of drugs. Nutritional intervention is the milestone treatment for patients with hypertriglyceridemia and it has to be modulated on the underlying cause and on triglyceride plasma levels. In pediatric patients, nutritional intervention must be tailored according to specific age-related energy, growth and neurodevelopment requests. Nutritional intervention is extremely strict in case of severe hypertriglyceridemia, whereas it is similar to good healthy nutritional habits counselling for mild forms, mainly related to wrong habits and lifestyles, and to secondary causes. The aim of this narrative review is to define different nutritional intervention for various forms of hypertriglyceridemia in children and adolescents.https://www.mdpi.com/2072-6643/15/5/1088hypertriglyceridemianutritionchildhoodpediatricsoverweight
spellingShingle Maria Elena Capra
Giacomo Biasucci
Giuseppe Banderali
Cristina Pederiva
Nutritional Treatment of Hypertriglyceridemia in Childhood: From Healthy-Heart Counselling to Life-Saving Diet
Nutrients
hypertriglyceridemia
nutrition
childhood
pediatrics
overweight
title Nutritional Treatment of Hypertriglyceridemia in Childhood: From Healthy-Heart Counselling to Life-Saving Diet
title_full Nutritional Treatment of Hypertriglyceridemia in Childhood: From Healthy-Heart Counselling to Life-Saving Diet
title_fullStr Nutritional Treatment of Hypertriglyceridemia in Childhood: From Healthy-Heart Counselling to Life-Saving Diet
title_full_unstemmed Nutritional Treatment of Hypertriglyceridemia in Childhood: From Healthy-Heart Counselling to Life-Saving Diet
title_short Nutritional Treatment of Hypertriglyceridemia in Childhood: From Healthy-Heart Counselling to Life-Saving Diet
title_sort nutritional treatment of hypertriglyceridemia in childhood from healthy heart counselling to life saving diet
topic hypertriglyceridemia
nutrition
childhood
pediatrics
overweight
url https://www.mdpi.com/2072-6643/15/5/1088
work_keys_str_mv AT mariaelenacapra nutritionaltreatmentofhypertriglyceridemiainchildhoodfromhealthyheartcounsellingtolifesavingdiet
AT giacomobiasucci nutritionaltreatmentofhypertriglyceridemiainchildhoodfromhealthyheartcounsellingtolifesavingdiet
AT giuseppebanderali nutritionaltreatmentofhypertriglyceridemiainchildhoodfromhealthyheartcounsellingtolifesavingdiet
AT cristinapederiva nutritionaltreatmentofhypertriglyceridemiainchildhoodfromhealthyheartcounsellingtolifesavingdiet