Investigation of Susceptibility of Methicillin Resistant Staphylococcus aureus Strains to Fusidic Acid and Trimethoprim-Sulfamethoxazole with Disc Diffusion Method
Development of resistance to Staphylococcus aureus which is one of the most important reasons of hospital and community acquired infections, causes difficulties in treatment of infections caused by this microorganism. Glycopeptide antibiotics and alternative agents including fusidic acid and trimeth...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Bilimsel Tip Yayinevi
2007-09-01
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| Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| Subjects: | |
| Online Access: | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2007-12-3-153-156.pdf |
| _version_ | 1797919043659759616 |
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| author | Serap İSKENDER Gürdal YILMAZ Kemalettin AYDIN Nurgün SUCU Gönülden AKTOZ BOZ Rahmet ÇAYLAN İftihar KÖKSAL |
| author_facet | Serap İSKENDER Gürdal YILMAZ Kemalettin AYDIN Nurgün SUCU Gönülden AKTOZ BOZ Rahmet ÇAYLAN İftihar KÖKSAL |
| author_sort | Serap İSKENDER |
| collection | DOAJ |
| description | Development of resistance to Staphylococcus aureus which is one of the most important reasons of hospital and community acquired infections, causes difficulties in treatment of infections caused by this microorganism. Glycopeptide antibiotics and alternative agents including fusidic acid and trimethoprim-sulfamethoxazole (TMP-SMX) can be used to treat methicillin resistant S. aureus (MRSA) infections. In this study, 292 MRSA strains, isolated from various clinical specimens of hospitalized patients in Karadeniz Technical University Medical Faculty Farabi Hospital, were evaluated for their susceptibilities to fusidic acid and TMPSMX by disk diffusion method. Susceptibility rates were 82.2% (240/292) for fusidic acid and 92.5% (270/292) for TMP-SMX. These antibiotics seem to be alternative agents especially for long term and consecutive treatment of MRSA infections. |
| first_indexed | 2024-04-10T13:39:11Z |
| format | Article |
| id | doaj.art-a1e05a10dc434144b4391c7937ee4127 |
| institution | Directory Open Access Journal |
| issn | 1300-932X 1300-932X |
| language | English |
| last_indexed | 2024-04-10T13:39:11Z |
| publishDate | 2007-09-01 |
| publisher | Bilimsel Tip Yayinevi |
| record_format | Article |
| series | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| spelling | doaj.art-a1e05a10dc434144b4391c7937ee41272023-02-15T16:11:16ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X1300-932X2007-09-01123153156Investigation of Susceptibility of Methicillin Resistant Staphylococcus aureus Strains to Fusidic Acid and Trimethoprim-Sulfamethoxazole with Disc Diffusion MethodSerap İSKENDER0Gürdal YILMAZ1Kemalettin AYDIN2Nurgün SUCU3Gönülden AKTOZ BOZ4Rahmet ÇAYLAN5İftihar KÖKSAL6Karadeniz Teknik Üniversitesi Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, TRABZONKaradeniz Teknik Üniversitesi Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, TRABZONKaradeniz Teknik Üniversitesi Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, TRABZONKaradeniz Teknik Üniversitesi Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, TRABZONKaradeniz Teknik Üniversitesi Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, TRABZONKaradeniz Teknik Üniversitesi Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, TRABZONKaradeniz Teknik Üniversitesi Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, TRABZONDevelopment of resistance to Staphylococcus aureus which is one of the most important reasons of hospital and community acquired infections, causes difficulties in treatment of infections caused by this microorganism. Glycopeptide antibiotics and alternative agents including fusidic acid and trimethoprim-sulfamethoxazole (TMP-SMX) can be used to treat methicillin resistant S. aureus (MRSA) infections. In this study, 292 MRSA strains, isolated from various clinical specimens of hospitalized patients in Karadeniz Technical University Medical Faculty Farabi Hospital, were evaluated for their susceptibilities to fusidic acid and TMPSMX by disk diffusion method. Susceptibility rates were 82.2% (240/292) for fusidic acid and 92.5% (270/292) for TMP-SMX. These antibiotics seem to be alternative agents especially for long term and consecutive treatment of MRSA infections.http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2007-12-3-153-156.pdfStaphylococcus aureusMethicillin resistanceFusidic acidTrimethoprim-sulfamethoxazole |
| spellingShingle | Serap İSKENDER Gürdal YILMAZ Kemalettin AYDIN Nurgün SUCU Gönülden AKTOZ BOZ Rahmet ÇAYLAN İftihar KÖKSAL Investigation of Susceptibility of Methicillin Resistant Staphylococcus aureus Strains to Fusidic Acid and Trimethoprim-Sulfamethoxazole with Disc Diffusion Method Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi Staphylococcus aureus Methicillin resistance Fusidic acid Trimethoprim-sulfamethoxazole |
| title | Investigation of Susceptibility of Methicillin Resistant Staphylococcus aureus Strains to Fusidic Acid and Trimethoprim-Sulfamethoxazole with Disc Diffusion Method |
| title_full | Investigation of Susceptibility of Methicillin Resistant Staphylococcus aureus Strains to Fusidic Acid and Trimethoprim-Sulfamethoxazole with Disc Diffusion Method |
| title_fullStr | Investigation of Susceptibility of Methicillin Resistant Staphylococcus aureus Strains to Fusidic Acid and Trimethoprim-Sulfamethoxazole with Disc Diffusion Method |
| title_full_unstemmed | Investigation of Susceptibility of Methicillin Resistant Staphylococcus aureus Strains to Fusidic Acid and Trimethoprim-Sulfamethoxazole with Disc Diffusion Method |
| title_short | Investigation of Susceptibility of Methicillin Resistant Staphylococcus aureus Strains to Fusidic Acid and Trimethoprim-Sulfamethoxazole with Disc Diffusion Method |
| title_sort | investigation of susceptibility of methicillin resistant staphylococcus aureus strains to fusidic acid and trimethoprim sulfamethoxazole with disc diffusion method |
| topic | Staphylococcus aureus Methicillin resistance Fusidic acid Trimethoprim-sulfamethoxazole |
| url | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2007-12-3-153-156.pdf |
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