Pediatric diencephalic tumors: a constellation of entities and management modalities

The diencephalon is a complex midline structure consisting of the hypothalamus, neurohypophysis, subthalamus, thalamus, epithalamus, and pineal body. Tumors arising from each of these diencephalic components differ significantly in terms of biology and prognosis. The aim of this comprehensive review...

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Main Authors: Soniya N. Pinto, Jason Chiang, Ibrahim Qaddoumi, David Livingston, Asim Bag
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1180267/full
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author Soniya N. Pinto
Jason Chiang
Ibrahim Qaddoumi
David Livingston
Asim Bag
author_facet Soniya N. Pinto
Jason Chiang
Ibrahim Qaddoumi
David Livingston
Asim Bag
author_sort Soniya N. Pinto
collection DOAJ
description The diencephalon is a complex midline structure consisting of the hypothalamus, neurohypophysis, subthalamus, thalamus, epithalamus, and pineal body. Tumors arising from each of these diencephalic components differ significantly in terms of biology and prognosis. The aim of this comprehensive review is to describe the epidemiology, clinical symptoms, imaging, histology, and molecular markers in the context of the 2021 WHO classification of central nervous system neoplasms. We will also discuss the current management of each of these tumors.
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spelling doaj.art-a1e0d879fb744fe0b11e8a152402b03e2023-07-13T15:01:29ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-07-011310.3389/fonc.2023.11802671180267Pediatric diencephalic tumors: a constellation of entities and management modalitiesSoniya N. Pinto0Jason Chiang1Ibrahim Qaddoumi2David Livingston3Asim Bag4Department of Diagnostic Imaging, St. Jude Children’s Research Hospital, Memphis, TN, United StatesDepartment of Pathology, St. Jude Children’s Research Hospital, Memphis, TN, United StatesDepartments of Global Pediatric Medicine, St. Jude Children’s Research Hospital, Memphis, TN, United StatesDepartment of Radiology, University of Tennessee Health Science Center, Memphis, TN, United StatesDepartment of Diagnostic Imaging, St. Jude Children’s Research Hospital, Memphis, TN, United StatesThe diencephalon is a complex midline structure consisting of the hypothalamus, neurohypophysis, subthalamus, thalamus, epithalamus, and pineal body. Tumors arising from each of these diencephalic components differ significantly in terms of biology and prognosis. The aim of this comprehensive review is to describe the epidemiology, clinical symptoms, imaging, histology, and molecular markers in the context of the 2021 WHO classification of central nervous system neoplasms. We will also discuss the current management of each of these tumors.https://www.frontiersin.org/articles/10.3389/fonc.2023.1180267/fulladenomacraniopharyngiomadiencephalongerm cell tumorlangerhans cell histiocytosispineoblastoma
spellingShingle Soniya N. Pinto
Jason Chiang
Ibrahim Qaddoumi
David Livingston
Asim Bag
Pediatric diencephalic tumors: a constellation of entities and management modalities
Frontiers in Oncology
adenoma
craniopharyngioma
diencephalon
germ cell tumor
langerhans cell histiocytosis
pineoblastoma
title Pediatric diencephalic tumors: a constellation of entities and management modalities
title_full Pediatric diencephalic tumors: a constellation of entities and management modalities
title_fullStr Pediatric diencephalic tumors: a constellation of entities and management modalities
title_full_unstemmed Pediatric diencephalic tumors: a constellation of entities and management modalities
title_short Pediatric diencephalic tumors: a constellation of entities and management modalities
title_sort pediatric diencephalic tumors a constellation of entities and management modalities
topic adenoma
craniopharyngioma
diencephalon
germ cell tumor
langerhans cell histiocytosis
pineoblastoma
url https://www.frontiersin.org/articles/10.3389/fonc.2023.1180267/full
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