Role of therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: an experience

Hypertriglyceridemia of obesity, the metabolic syndrome, and type II diabetes mellitus are highly prevalent in Saudi Arabia. Severe hypertriglyceridemia is a rare but well known cause of acute pancreatitis. In treatment pancreatic rest, lifestyle changes, and lipid-lowering medications are essential...

Full description

Bibliographic Details
Main Authors: Shaikh Ahmed Muntajib Wassay, Farhan Javed Dar, Asem K. Saleh, Ibrahim Mansoor
Format: Article
Language:English
Published: SAGE Publishing 2017-12-01
Series:Therapeutic Advances in Endocrinology and Metabolism
Online Access:https://doi.org/10.1177/2042018817739571
_version_ 1828759096736612352
author Shaikh Ahmed Muntajib Wassay
Farhan Javed Dar
Asem K. Saleh
Ibrahim Mansoor
author_facet Shaikh Ahmed Muntajib Wassay
Farhan Javed Dar
Asem K. Saleh
Ibrahim Mansoor
author_sort Shaikh Ahmed Muntajib Wassay
collection DOAJ
description Hypertriglyceridemia of obesity, the metabolic syndrome, and type II diabetes mellitus are highly prevalent in Saudi Arabia. Severe hypertriglyceridemia is a rare but well known cause of acute pancreatitis. In treatment pancreatic rest, lifestyle changes, and lipid-lowering medications are essential, but the response is slow. Recently the role of therapeutic plasma exchange (TPE) has been stressed for fast and effective management in addition to insulin and heparin infusion. TPE for hypertriglyceridemic pancreatitis resulted in drastic improvements in clinical and laboratory findings and patient outcomes as suggested in our cases. However, this procedure is limited due to its high cost and availability only in specialized hospitals.
first_indexed 2024-12-11T00:52:10Z
format Article
id doaj.art-a1e4db1c54d5456fb1807051adee2de9
institution Directory Open Access Journal
issn 2042-0188
2042-0196
language English
last_indexed 2024-12-11T00:52:10Z
publishDate 2017-12-01
publisher SAGE Publishing
record_format Article
series Therapeutic Advances in Endocrinology and Metabolism
spelling doaj.art-a1e4db1c54d5456fb1807051adee2de92022-12-22T01:26:35ZengSAGE PublishingTherapeutic Advances in Endocrinology and Metabolism2042-01882042-01962017-12-01810.1177/2042018817739571Role of therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: an experienceShaikh Ahmed Muntajib WassayFarhan Javed DarAsem K. SalehIbrahim MansoorHypertriglyceridemia of obesity, the metabolic syndrome, and type II diabetes mellitus are highly prevalent in Saudi Arabia. Severe hypertriglyceridemia is a rare but well known cause of acute pancreatitis. In treatment pancreatic rest, lifestyle changes, and lipid-lowering medications are essential, but the response is slow. Recently the role of therapeutic plasma exchange (TPE) has been stressed for fast and effective management in addition to insulin and heparin infusion. TPE for hypertriglyceridemic pancreatitis resulted in drastic improvements in clinical and laboratory findings and patient outcomes as suggested in our cases. However, this procedure is limited due to its high cost and availability only in specialized hospitals.https://doi.org/10.1177/2042018817739571
spellingShingle Shaikh Ahmed Muntajib Wassay
Farhan Javed Dar
Asem K. Saleh
Ibrahim Mansoor
Role of therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: an experience
Therapeutic Advances in Endocrinology and Metabolism
title Role of therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: an experience
title_full Role of therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: an experience
title_fullStr Role of therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: an experience
title_full_unstemmed Role of therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: an experience
title_short Role of therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: an experience
title_sort role of therapeutic plasma exchange in the treatment of severe hypertriglyceridemia an experience
url https://doi.org/10.1177/2042018817739571
work_keys_str_mv AT shaikhahmedmuntajibwassay roleoftherapeuticplasmaexchangeinthetreatmentofseverehypertriglyceridemiaanexperience
AT farhanjaveddar roleoftherapeuticplasmaexchangeinthetreatmentofseverehypertriglyceridemiaanexperience
AT asemksaleh roleoftherapeuticplasmaexchangeinthetreatmentofseverehypertriglyceridemiaanexperience
AT ibrahimmansoor roleoftherapeuticplasmaexchangeinthetreatmentofseverehypertriglyceridemiaanexperience