Incremental value of left atrial strain to predict atrial fibrillation recurrence after cryoballoon ablation
<h4>Objective</h4> Atrial fibrillation (AF) recurrence occurs in approximately 25% of the patients undergoing cryoballoon ablation (CBA), leading to repeated ablations and complications. Left atrial (LA) dilation has been proposed as a predictor of AF recurrence. However, LA strain is a...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604362/?tool=EBI |
| _version_ | 1818980566257631232 |
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| author | Andreea Motoc Maria–Luiza Luchian Esther Scheirlynck Bram Roosens Hadischat Chameleva Maxim Gevers Xavier Galloo Berlinde von Kemp Robbert Ramak Juan Sieira Carlo de Asmundis Gian–Battista Chierchia Julien Magne Caroline Weytjens Steven Droogmans Bernard Cosyns |
| author_facet | Andreea Motoc Maria–Luiza Luchian Esther Scheirlynck Bram Roosens Hadischat Chameleva Maxim Gevers Xavier Galloo Berlinde von Kemp Robbert Ramak Juan Sieira Carlo de Asmundis Gian–Battista Chierchia Julien Magne Caroline Weytjens Steven Droogmans Bernard Cosyns |
| author_sort | Andreea Motoc |
| collection | DOAJ |
| description | <h4>Objective</h4> Atrial fibrillation (AF) recurrence occurs in approximately 25% of the patients undergoing cryoballoon ablation (CBA), leading to repeated ablations and complications. Left atrial (LA) dilation has been proposed as a predictor of AF recurrence. However, LA strain is a surrogate marker of LA mechanical dysfunction, which might appear before the enlargement of the LA. The purpose of this study was to evaluate the additional predictive value of LA function assessed using strain echocardiography for AF recurrence after CBA. <h4>Methods</h4> 172 consecutive patients (62.2 ± 12.2 years, 61% male) were prospectively analyzed. Echocardiography was performed before CBA. Blanking period was defined as the first three months post-ablation. The primary endpoint was AF recurrence after the blanking period. <h4>Results</h4> 50 (29%) patients had AF recurrence. In the overall study population, peak atrial longitudinal strain (PALS) ≤ 17% had the highest incremental predictive value for AF recurrence (HR = 9.45, 95%CI: 3.17–28.13, p < 0.001). In patients with non-dilated LA, PALS≤17% remained an independent predictor of AF recurrence (HR = 5.39, 95%CI: 1.66–17.52, p = 0.005). <h4>Conclusions</h4> This study showed that LA function assessed by PALS provided an additional predictive value for AF recurrence after CBA, over LA enlargement. In patients with non—dilated LA, PALS also predicted AF recurrence. These findings emphasize the added value of LA strain, suggesting that it should be implemented in the systematic evaluation of AF patients before CBA. |
| first_indexed | 2024-12-20T17:17:28Z |
| format | Article |
| id | doaj.art-a1e5d63148334b0bbc89ad2d0d1d036f |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T17:17:28Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-a1e5d63148334b0bbc89ad2d0d1d036f2022-12-21T19:31:57ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-011611Incremental value of left atrial strain to predict atrial fibrillation recurrence after cryoballoon ablationAndreea MotocMaria–Luiza LuchianEsther ScheirlynckBram RoosensHadischat ChamelevaMaxim GeversXavier GallooBerlinde von KempRobbert RamakJuan SieiraCarlo de AsmundisGian–Battista ChierchiaJulien MagneCaroline WeytjensSteven DroogmansBernard Cosyns<h4>Objective</h4> Atrial fibrillation (AF) recurrence occurs in approximately 25% of the patients undergoing cryoballoon ablation (CBA), leading to repeated ablations and complications. Left atrial (LA) dilation has been proposed as a predictor of AF recurrence. However, LA strain is a surrogate marker of LA mechanical dysfunction, which might appear before the enlargement of the LA. The purpose of this study was to evaluate the additional predictive value of LA function assessed using strain echocardiography for AF recurrence after CBA. <h4>Methods</h4> 172 consecutive patients (62.2 ± 12.2 years, 61% male) were prospectively analyzed. Echocardiography was performed before CBA. Blanking period was defined as the first three months post-ablation. The primary endpoint was AF recurrence after the blanking period. <h4>Results</h4> 50 (29%) patients had AF recurrence. In the overall study population, peak atrial longitudinal strain (PALS) ≤ 17% had the highest incremental predictive value for AF recurrence (HR = 9.45, 95%CI: 3.17–28.13, p < 0.001). In patients with non-dilated LA, PALS≤17% remained an independent predictor of AF recurrence (HR = 5.39, 95%CI: 1.66–17.52, p = 0.005). <h4>Conclusions</h4> This study showed that LA function assessed by PALS provided an additional predictive value for AF recurrence after CBA, over LA enlargement. In patients with non—dilated LA, PALS also predicted AF recurrence. These findings emphasize the added value of LA strain, suggesting that it should be implemented in the systematic evaluation of AF patients before CBA.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604362/?tool=EBI |
| spellingShingle | Andreea Motoc Maria–Luiza Luchian Esther Scheirlynck Bram Roosens Hadischat Chameleva Maxim Gevers Xavier Galloo Berlinde von Kemp Robbert Ramak Juan Sieira Carlo de Asmundis Gian–Battista Chierchia Julien Magne Caroline Weytjens Steven Droogmans Bernard Cosyns Incremental value of left atrial strain to predict atrial fibrillation recurrence after cryoballoon ablation PLoS ONE |
| title | Incremental value of left atrial strain to predict atrial fibrillation recurrence after cryoballoon ablation |
| title_full | Incremental value of left atrial strain to predict atrial fibrillation recurrence after cryoballoon ablation |
| title_fullStr | Incremental value of left atrial strain to predict atrial fibrillation recurrence after cryoballoon ablation |
| title_full_unstemmed | Incremental value of left atrial strain to predict atrial fibrillation recurrence after cryoballoon ablation |
| title_short | Incremental value of left atrial strain to predict atrial fibrillation recurrence after cryoballoon ablation |
| title_sort | incremental value of left atrial strain to predict atrial fibrillation recurrence after cryoballoon ablation |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604362/?tool=EBI |
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