The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression
Summary: AXL is activated by its ligand GAS6 and is expressed in triple-negative breast cancer cells. In the current study, we report AXL expression in HER2-positive (HER2+) breast cancers where it correlates with poor patient survival. Using murine models of HER2+ breast cancer, Axl, but not its li...
Հիմնական հեղինակներ: | , , , , , , , , , , , , , , |
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Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
Elsevier
2018-05-01
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Շարք: | Cell Reports |
Առցանց հասանելիություն: | http://www.sciencedirect.com/science/article/pii/S2211124718305485 |