Long-term prognosis of patients with stroke associated with middle cerebral artery occlusion. Single-centre registration study
Introduction Large artery intracranial occlusive disease including middle cerebral artery (MCA) is a major contributor to the incidence of stroke in China. The data on the prognosis of symptomatic atherosclerotic MCA occlusions (MCAO) are limited. We aimed to investigate the related factors of unfav...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2019-08-01
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| Series: | Archives of Medical Science |
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| Online Access: | https://www.archivesofmedicalscience.com/Long-term-prognosis-of-patients-with-stroke-associated-with-middle-cerebral-artery,109255,0,2.html |
| _version_ | 1827620384793427968 |
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| author | Bin Chen Yufang Sun Zheng Wei Yongbo Zhang |
| author_facet | Bin Chen Yufang Sun Zheng Wei Yongbo Zhang |
| author_sort | Bin Chen |
| collection | DOAJ |
| description | Introduction
Large artery intracranial occlusive disease including middle cerebral artery (MCA) is a major contributor to the incidence of stroke in China. The data on the prognosis of symptomatic atherosclerotic MCA occlusions (MCAO) are limited. We aimed to investigate the related factors of unfavorable outcomes in patients with stroke associated with MCAO.
Material and methods
A total of 119 patients with MCAO symptom were enrolled in this retrospective longitudinal cohort study. All patients met inclusion criteria of cerebral angiography by CT angiography or magnetic resonance angiography. Stroke severity was assessed on admission using the National Institutes of Health Stroke Scale (NIHSS) and modified Rankin Scale (mRS).
Results
We showed an average follow-up time of 46.8 months, within which 20 (19.6%) cases died and 14 (13.7%) cases had stroke recurrence. Using mRS as an evaluation index, the patients were divided into an unfavourable outcome group (mRS > 2, 48 cases) and a favourable outcome group (mRS ≤ 2, 54 cases). Logistic regression analysis suggests that age and NIHSS score were independent risk factors for a poor outcome value. Coexisting other cerebral vascular occlusion was an independent risk factor for stroke recurrence. Age was an independent risk factor for death.
Conclusions
The prognosis of patients with MCAO was generally optimistic, with higher survival rate and longer survival time. As compared, elder age and higher NIHSS score both tend to be associated with worse prognosis of survival. MCAO patients with other extracranial or intracranial vascular occlusion have higher risk of recurrent stroke. Death rate increases with age among the MCAO patients. |
| first_indexed | 2024-03-09T10:46:43Z |
| format | Article |
| id | doaj.art-a1eb862a824a4414ada17891827c212b |
| institution | Directory Open Access Journal |
| issn | 1734-1922 1896-9151 |
| language | English |
| last_indexed | 2024-03-09T10:46:43Z |
| publishDate | 2019-08-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Archives of Medical Science |
| spelling | doaj.art-a1eb862a824a4414ada17891827c212b2023-12-01T10:00:43ZengTermedia Publishing HouseArchives of Medical Science1734-19221896-91512019-08-011851199120710.5114/aoms.2019.87129109255Long-term prognosis of patients with stroke associated with middle cerebral artery occlusion. Single-centre registration studyBin Chen0Yufang Sun1Zheng Wei2Yongbo Zhang3Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaDepartment of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaDepartment of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaDepartment of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaIntroduction Large artery intracranial occlusive disease including middle cerebral artery (MCA) is a major contributor to the incidence of stroke in China. The data on the prognosis of symptomatic atherosclerotic MCA occlusions (MCAO) are limited. We aimed to investigate the related factors of unfavorable outcomes in patients with stroke associated with MCAO. Material and methods A total of 119 patients with MCAO symptom were enrolled in this retrospective longitudinal cohort study. All patients met inclusion criteria of cerebral angiography by CT angiography or magnetic resonance angiography. Stroke severity was assessed on admission using the National Institutes of Health Stroke Scale (NIHSS) and modified Rankin Scale (mRS). Results We showed an average follow-up time of 46.8 months, within which 20 (19.6%) cases died and 14 (13.7%) cases had stroke recurrence. Using mRS as an evaluation index, the patients were divided into an unfavourable outcome group (mRS > 2, 48 cases) and a favourable outcome group (mRS ≤ 2, 54 cases). Logistic regression analysis suggests that age and NIHSS score were independent risk factors for a poor outcome value. Coexisting other cerebral vascular occlusion was an independent risk factor for stroke recurrence. Age was an independent risk factor for death. Conclusions The prognosis of patients with MCAO was generally optimistic, with higher survival rate and longer survival time. As compared, elder age and higher NIHSS score both tend to be associated with worse prognosis of survival. MCAO patients with other extracranial or intracranial vascular occlusion have higher risk of recurrent stroke. Death rate increases with age among the MCAO patients.https://www.archivesofmedicalscience.com/Long-term-prognosis-of-patients-with-stroke-associated-with-middle-cerebral-artery,109255,0,2.htmlmiddle cerebral artery occlusionrisk factorsprognosisdeathmodified rankin scalestroke recurrence |
| spellingShingle | Bin Chen Yufang Sun Zheng Wei Yongbo Zhang Long-term prognosis of patients with stroke associated with middle cerebral artery occlusion. Single-centre registration study Archives of Medical Science middle cerebral artery occlusion risk factors prognosis death modified rankin scale stroke recurrence |
| title | Long-term prognosis of patients with stroke associated with middle cerebral artery occlusion. Single-centre registration study |
| title_full | Long-term prognosis of patients with stroke associated with middle cerebral artery occlusion. Single-centre registration study |
| title_fullStr | Long-term prognosis of patients with stroke associated with middle cerebral artery occlusion. Single-centre registration study |
| title_full_unstemmed | Long-term prognosis of patients with stroke associated with middle cerebral artery occlusion. Single-centre registration study |
| title_short | Long-term prognosis of patients with stroke associated with middle cerebral artery occlusion. Single-centre registration study |
| title_sort | long term prognosis of patients with stroke associated with middle cerebral artery occlusion single centre registration study |
| topic | middle cerebral artery occlusion risk factors prognosis death modified rankin scale stroke recurrence |
| url | https://www.archivesofmedicalscience.com/Long-term-prognosis-of-patients-with-stroke-associated-with-middle-cerebral-artery,109255,0,2.html |
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