Integrated lipidomics and proteomics network analysis highlights lipid and immunity pathways associated with Alzheimer’s disease

Integrated lipidomics and proteomics network analysis highlights lipid and immunity pathways associated with Alzheimer’s disease

Abstract Background There is an urgent need to understand the pathways and processes underlying Alzheimer’s disease (AD) for early diagnosis and development of effective treatments. This study was aimed to investigate Alzheimer’s dementia using an unsupervised lipid, protein and gene multi-omics int...

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Bibliographic Details
Main Authors: Jin Xu, Giulia Bankov, Min Kim, Asger Wretlind, Jodie Lord, Rebecca Green, Angela Hodges, Abdul Hye, Dag Aarsland, Latha Velayudhan, Richard J. B. Dobson, Petroula Proitsi, Cristina Legido-Quigley, on behalf of the AddNeuroMed Consortium
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Translational Neurodegeneration
Subjects:
Alzheimer’s disease
Dementia
Brain atrophy
sMRI
Rate of cognitive decline
Lipidomics
Online Access:http://link.springer.com/article/10.1186/s40035-020-00215-0

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