Dataset on inflammatory proteins expressions and sialic acid levels in apolipoprotein E-deficient mice with administration of N-acetylneuraminic acid and/or quercetin
The data presented in this article describe an effect of N-acetylneuraminic acid and/or quercetin on the inflammatory proteins expressions (TNF-α, ICAM-1, VCAM-1 and MOMA-2) and the N-acetylneuraminic acid (NANA) levels of apolipoprotein E-deficient mice that are given a high-fat diet. Protein expre...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2016-09-01
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| Series: | Data in Brief |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340916303882 |
| _version_ | 1819261135178694656 |
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| author | Rongrong Dong Fahui Li Shucun Qin Yi Wang Yanhong Si Xuelian Xu Hua Tian Lei Zhai Guangjie Zhang Yongjun Li Yawei Zhou Ying Zhang Nan Zhang Shoudong Guo |
| author_facet | Rongrong Dong Fahui Li Shucun Qin Yi Wang Yanhong Si Xuelian Xu Hua Tian Lei Zhai Guangjie Zhang Yongjun Li Yawei Zhou Ying Zhang Nan Zhang Shoudong Guo |
| author_sort | Rongrong Dong |
| collection | DOAJ |
| description | The data presented in this article describe an effect of N-acetylneuraminic acid and/or quercetin on the inflammatory proteins expressions (TNF-α, ICAM-1, VCAM-1 and MOMA-2) and the N-acetylneuraminic acid (NANA) levels of apolipoprotein E-deficient mice that are given a high-fat diet. Protein expression was performed by immunohistochemical imaging and NANA was quantified by liquid chromatography-tandem mass spectrometry (LC-MS/MS) or semi-quantified using Image-Pro Plus software after ligation with fluorescein-5-thiosemicarbazide (FTSC). Further interpretation and discussion could be found at our research article entitled “Exogenous supplement of N-acetylneuraminic acid ameliorates atherosclerosis in apolipoprotein E-deficient mice” (Guo et al., 2016) [1]. Keywords: Immunohistochemistry, LC-MS/MS, Sialic acid, Fluorescent labeling, Imaging |
| first_indexed | 2024-12-23T19:36:59Z |
| format | Article |
| id | doaj.art-a1ecd36945a6490a86929ab8129bde3e |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-12-23T19:36:59Z |
| publishDate | 2016-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-a1ecd36945a6490a86929ab8129bde3e2022-12-21T17:33:46ZengElsevierData in Brief2352-34092016-09-018613617Dataset on inflammatory proteins expressions and sialic acid levels in apolipoprotein E-deficient mice with administration of N-acetylneuraminic acid and/or quercetinRongrong Dong0Fahui Li1Shucun Qin2Yi Wang3Yanhong Si4Xuelian Xu5Hua Tian6Lei Zhai7Guangjie Zhang8Yongjun Li9Yawei Zhou10Ying Zhang11Nan Zhang12Shoudong Guo13Key Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, ChinaDepartment of Chemistry and Chemical Engineering, Weifang University, Weifang 261061, ChinaKey Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, ChinaDepartment of Ophthalmology, Affilated Hospital of Taishan Medical University, Taian 271000, ChinaKey Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, ChinaSchool of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, ChinaKey Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, ChinaKey Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, ChinaKey Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, ChinaKey Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, ChinaKey Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, ChinaKey Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, ChinaKey Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, ChinaKey Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, China; Corresponding author. Fax: +86 0538 6225275.The data presented in this article describe an effect of N-acetylneuraminic acid and/or quercetin on the inflammatory proteins expressions (TNF-α, ICAM-1, VCAM-1 and MOMA-2) and the N-acetylneuraminic acid (NANA) levels of apolipoprotein E-deficient mice that are given a high-fat diet. Protein expression was performed by immunohistochemical imaging and NANA was quantified by liquid chromatography-tandem mass spectrometry (LC-MS/MS) or semi-quantified using Image-Pro Plus software after ligation with fluorescein-5-thiosemicarbazide (FTSC). Further interpretation and discussion could be found at our research article entitled “Exogenous supplement of N-acetylneuraminic acid ameliorates atherosclerosis in apolipoprotein E-deficient mice” (Guo et al., 2016) [1]. Keywords: Immunohistochemistry, LC-MS/MS, Sialic acid, Fluorescent labeling, Imaginghttp://www.sciencedirect.com/science/article/pii/S2352340916303882 |
| spellingShingle | Rongrong Dong Fahui Li Shucun Qin Yi Wang Yanhong Si Xuelian Xu Hua Tian Lei Zhai Guangjie Zhang Yongjun Li Yawei Zhou Ying Zhang Nan Zhang Shoudong Guo Dataset on inflammatory proteins expressions and sialic acid levels in apolipoprotein E-deficient mice with administration of N-acetylneuraminic acid and/or quercetin Data in Brief |
| title | Dataset on inflammatory proteins expressions and sialic acid levels in apolipoprotein E-deficient mice with administration of N-acetylneuraminic acid and/or quercetin |
| title_full | Dataset on inflammatory proteins expressions and sialic acid levels in apolipoprotein E-deficient mice with administration of N-acetylneuraminic acid and/or quercetin |
| title_fullStr | Dataset on inflammatory proteins expressions and sialic acid levels in apolipoprotein E-deficient mice with administration of N-acetylneuraminic acid and/or quercetin |
| title_full_unstemmed | Dataset on inflammatory proteins expressions and sialic acid levels in apolipoprotein E-deficient mice with administration of N-acetylneuraminic acid and/or quercetin |
| title_short | Dataset on inflammatory proteins expressions and sialic acid levels in apolipoprotein E-deficient mice with administration of N-acetylneuraminic acid and/or quercetin |
| title_sort | dataset on inflammatory proteins expressions and sialic acid levels in apolipoprotein e deficient mice with administration of n acetylneuraminic acid and or quercetin |
| url | http://www.sciencedirect.com/science/article/pii/S2352340916303882 |
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