The comparison of manual and mechanical anastomosis after total pharyngolaryngoesophagectomy
BackgroundTotal pharyngolaryngoesophagectomy (TPLE) is considered as a curative treatment for hypopharynx cancer and cervical esophageal carcinomas (HPCECs). Traditional pharyngo-gastric anastomosis is usually performed manually, and postoperative complications are common. The aim of this study was...
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| Format: | Article |
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1041396/full |
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| author | Kexi Wang Kexi Wang Xiaotian He Xiaotian He Duoguang Wu Duoguang Wu Kefeng Wang Kefeng Wang Yuquan Li Yuquan Li Wenjian Wang Wenjian Wang Xueting Hu Xueting Hu Kai Lei Kai Lei Binghua Tan Binghua Tan Ruihao Liang Ruihao Liang Qian Cai Qian Cai Minghui Wang Minghui Wang |
| author_facet | Kexi Wang Kexi Wang Xiaotian He Xiaotian He Duoguang Wu Duoguang Wu Kefeng Wang Kefeng Wang Yuquan Li Yuquan Li Wenjian Wang Wenjian Wang Xueting Hu Xueting Hu Kai Lei Kai Lei Binghua Tan Binghua Tan Ruihao Liang Ruihao Liang Qian Cai Qian Cai Minghui Wang Minghui Wang |
| author_sort | Kexi Wang |
| collection | DOAJ |
| description | BackgroundTotal pharyngolaryngoesophagectomy (TPLE) is considered as a curative treatment for hypopharynx cancer and cervical esophageal carcinomas (HPCECs). Traditional pharyngo-gastric anastomosis is usually performed manually, and postoperative complications are common. The aim of this study was to introduce a new technique for mechanical anastomosis and to evaluate perioperative outcomes and prognosis.MethodsFrom May 1995 to Nov 2021, a series of 75 consecutive patients who received TPLE for a pathological diagnosis of HPCECs at Sun Yat-sen Memorial Hospital were evaluated. Mechanical anastomosis was performed in 28 cases and manual anastomosis was performed in 47 cases. The data from these patients were retrospectively analyzed.ResultsThe mean age was 57.6 years, and 20% of the patients were female. The rate of anastomotic fistula and wound infection in the mechanical group were significantly lower than that in the manual group. The operation time, intraoperative blood loss and postoperative hospital stays were significantly higher in the manual group than that in the mechanical group. The R0 resection rate and the tumor characteristics were not significantly different between groups. There was no significant difference in overall survival and disease-free survival between the two groups.ConclusionThe mechanical anastomosis technology adopted by this study was shown to be a safer and more effective procedure with similar survival comparable to that of manual anastomosis for the HPCECs patients. |
| first_indexed | 2024-04-10T07:04:06Z |
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| id | doaj.art-a1eef726aa0946d6957281be92df0dad |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-10T07:04:06Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-a1eef726aa0946d6957281be92df0dad2023-02-27T13:34:56ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-02-011310.3389/fonc.2023.10413961041396The comparison of manual and mechanical anastomosis after total pharyngolaryngoesophagectomyKexi Wang0Kexi Wang1Xiaotian He2Xiaotian He3Duoguang Wu4Duoguang Wu5Kefeng Wang6Kefeng Wang7Yuquan Li8Yuquan Li9Wenjian Wang10Wenjian Wang11Xueting Hu12Xueting Hu13Kai Lei14Kai Lei15Binghua Tan16Binghua Tan17Ruihao Liang18Ruihao Liang19Qian Cai20Qian Cai21Minghui Wang22Minghui Wang23Department of Thoracic Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Thoracic Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Thoracic Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Thoracic Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Thoracic Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Thoracic Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Thoracic Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Thoracic Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Thoracic Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Thoracic Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaDepartment of Otolaryngology Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, ChinaDepartment of Thoracic Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaBackgroundTotal pharyngolaryngoesophagectomy (TPLE) is considered as a curative treatment for hypopharynx cancer and cervical esophageal carcinomas (HPCECs). Traditional pharyngo-gastric anastomosis is usually performed manually, and postoperative complications are common. The aim of this study was to introduce a new technique for mechanical anastomosis and to evaluate perioperative outcomes and prognosis.MethodsFrom May 1995 to Nov 2021, a series of 75 consecutive patients who received TPLE for a pathological diagnosis of HPCECs at Sun Yat-sen Memorial Hospital were evaluated. Mechanical anastomosis was performed in 28 cases and manual anastomosis was performed in 47 cases. The data from these patients were retrospectively analyzed.ResultsThe mean age was 57.6 years, and 20% of the patients were female. The rate of anastomotic fistula and wound infection in the mechanical group were significantly lower than that in the manual group. The operation time, intraoperative blood loss and postoperative hospital stays were significantly higher in the manual group than that in the mechanical group. The R0 resection rate and the tumor characteristics were not significantly different between groups. There was no significant difference in overall survival and disease-free survival between the two groups.ConclusionThe mechanical anastomosis technology adopted by this study was shown to be a safer and more effective procedure with similar survival comparable to that of manual anastomosis for the HPCECs patients.https://www.frontiersin.org/articles/10.3389/fonc.2023.1041396/fulltotal pharyngolaryngoesophagectomyanastomosismanualmechanicalpostoperative complications |
| spellingShingle | Kexi Wang Kexi Wang Xiaotian He Xiaotian He Duoguang Wu Duoguang Wu Kefeng Wang Kefeng Wang Yuquan Li Yuquan Li Wenjian Wang Wenjian Wang Xueting Hu Xueting Hu Kai Lei Kai Lei Binghua Tan Binghua Tan Ruihao Liang Ruihao Liang Qian Cai Qian Cai Minghui Wang Minghui Wang The comparison of manual and mechanical anastomosis after total pharyngolaryngoesophagectomy Frontiers in Oncology total pharyngolaryngoesophagectomy anastomosis manual mechanical postoperative complications |
| title | The comparison of manual and mechanical anastomosis after total pharyngolaryngoesophagectomy |
| title_full | The comparison of manual and mechanical anastomosis after total pharyngolaryngoesophagectomy |
| title_fullStr | The comparison of manual and mechanical anastomosis after total pharyngolaryngoesophagectomy |
| title_full_unstemmed | The comparison of manual and mechanical anastomosis after total pharyngolaryngoesophagectomy |
| title_short | The comparison of manual and mechanical anastomosis after total pharyngolaryngoesophagectomy |
| title_sort | comparison of manual and mechanical anastomosis after total pharyngolaryngoesophagectomy |
| topic | total pharyngolaryngoesophagectomy anastomosis manual mechanical postoperative complications |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1041396/full |
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