Simultaneous enantioseparation and simulation studies of atenolol, metoprolol and propranolol on Chiralpak® IG column using supercritical fluid chromatography

Simultaneous enantioseparation and simulation studies of atenolol, metoprolol and propranolol on Chiralpak® IG column using supercritical fluid chromatography

Enantioseparation of three β-blockers, i.e., atenolol, metoprolol and propranolol, was studied on amylose tris(3-chloro-5-methylphenylcarbamate) immobilized chiral stationary phase using supercritical fluid chromatography (SFC). The effect of organic modifiers (methanol, isopropanol and their mixtur...

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Bibliographic Details
Main Authors:	Pranav A. Pandya, Priyanka A. Shah, Pranav S. Shrivastav
Format:	Article
Language:	English
Published:	Elsevier 2021-12-01
Series:	Journal of Pharmaceutical Analysis
Subjects:	Enantioseparation Supercritical fluid chromatography β-blockers Chiralpak® IG column Molecular docking Binding energy
Online Access:	http://www.sciencedirect.com/science/article/pii/S2095177920310996

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