Reprogramming of Amino Acid Metabolism Differs between Community-Acquired Pneumonia and Infection-Associated Exacerbation of Chronic Obstructive Pulmonary Disease

Reprogramming of Amino Acid Metabolism Differs between Community-Acquired Pneumonia and Infection-Associated Exacerbation of Chronic Obstructive Pulmonary Disease

Amino acids and their metabolites are key regulators of immune responses, and plasma levels may change profoundly during acute disease states. Using targeted metabolomics, we evaluated concentration changes in plasma amino acids and related metabolites in community-acquired pneumonia (CAP, <i>...

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Bibliographic Details
Main Authors: Haroon Arshad, Anastasios Siokis, Raimo Franke, Aamna Habib, Juan Carlos López Alfonso, Yuliya Poliakova, Eva Lücke, Katina Michaelis, Mark Brönstrup, Michael Meyer-Hermann, Ursula Bilitewski, Jordi Vila, Laurent Abel, Thomas Illig, Jens Schreiber, Frank Pessler
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cells
Subjects:
amino acids
biogenic amines
biomarkers
chronic obstructive pulmonary disease
diagnosis
inflammation
Online Access:https://www.mdpi.com/2073-4409/11/15/2283

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