Validity and reliability of the EQ-5D-5 L in family caregivers of leukemia patients
Abstract Purpose This study aimed to test the validity and reliability of the five-level EuroQol five-dimensional (EQ-5D-5 L) instrument in family caregivers (FCs) of leukemia patients in Heilongjiang of China. Methods A cross-sectional survey was conducted on 298 family caregivers (FCs) of leukemia...
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| Format: | Article |
| Language: | English |
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BMC
2019-05-01
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| Series: | BMC Cancer |
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| Online Access: | http://link.springer.com/article/10.1186/s12885-019-5721-2 |
| _version_ | 1818499055516385280 |
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| author | Limin Li Chaojie Liu Xiuzhi Cai Hongjuan Yu Xueyun Zeng Mingjie Sui Erwei Zheng Yang Li Jiao Xu Jin Zhou Weidong Huang |
| author_facet | Limin Li Chaojie Liu Xiuzhi Cai Hongjuan Yu Xueyun Zeng Mingjie Sui Erwei Zheng Yang Li Jiao Xu Jin Zhou Weidong Huang |
| author_sort | Limin Li |
| collection | DOAJ |
| description | Abstract Purpose This study aimed to test the validity and reliability of the five-level EuroQol five-dimensional (EQ-5D-5 L) instrument in family caregivers (FCs) of leukemia patients in Heilongjiang of China. Methods A cross-sectional survey was conducted on 298 family caregivers (FCs) of leukemia patients from three major cancer centers in the capital city of Heilongjiang province of China. Their dimensional scores of the EQ-5D-5 L were compared with those of the WHOQOL-BREF to test the convergent validity (constructs measuring the same concept) and divergent validity (constructs measuring different concepts) of the EQ-5D-5 L. Repeated surveys were conducted on 271 participants to determine the test–retest reliability of the EQ-5D-5 L. Results The four physical dimensions (mobility, self-care, usual activities, and pain/discomfort) of the EQ-5D-5 L had moderate or high correlations with the physical health domain of the WHOQOL-BREF, with a correlation coefficient (r) ranging from 0.459 to 0.559. The anxiety/depression dimension of the EQ-5D-5 L had a high correlation (r = 0.667) with the psychological domain of the WHOQOL-BREF. By contrast, lower but still significant physical-to-psychological correlations were found between the two instruments (r ranging from 0.219 to 0.396). In addition, the EQ-5D-5 L dimensional scores showed no or weak correlations with the environment and social domains of the WHOQOL-BREF (r ranging from 0.016 to 0.207). High test-retest reliability (> 0.7) was evident. Conclusion The Chinese version of the EQ-5D-5 L has satisfactory reliability and validity in FCs of leukemia patients. It can be used to elicit utility of health-related quality of life in FCs of leukemia. |
| first_indexed | 2024-12-10T20:24:03Z |
| format | Article |
| id | doaj.art-a1f879470d4a437888c09350a5c6ede2 |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-12-10T20:24:03Z |
| publishDate | 2019-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-a1f879470d4a437888c09350a5c6ede22022-12-22T01:34:56ZengBMCBMC Cancer1471-24072019-05-011911910.1186/s12885-019-5721-2Validity and reliability of the EQ-5D-5 L in family caregivers of leukemia patientsLimin Li0Chaojie Liu1Xiuzhi Cai2Hongjuan Yu3Xueyun Zeng4Mingjie Sui5Erwei Zheng6Yang Li7Jiao Xu8Jin Zhou9Weidong Huang10First Affiliated Hospital of Harbin Medical UniversitySchool of Psychology and Public Health, La Trobe UniversityHarbin center for disease control and preventionFirst Affiliated Hospital of Harbin Medical UniversitySchool of Health Management, Harbin Medical UniversitySchool of Health Management, Harbin Medical UniversityFirst Affiliated Hospital of Harbin Medical UniversityFirst Affiliated Hospital of Harbin Medical UniversityFirst Affiliated Hospital of Harbin Medical UniversityFirst Affiliated Hospital of Harbin Medical UniversitySchool of Health Management, Harbin Medical UniversityAbstract Purpose This study aimed to test the validity and reliability of the five-level EuroQol five-dimensional (EQ-5D-5 L) instrument in family caregivers (FCs) of leukemia patients in Heilongjiang of China. Methods A cross-sectional survey was conducted on 298 family caregivers (FCs) of leukemia patients from three major cancer centers in the capital city of Heilongjiang province of China. Their dimensional scores of the EQ-5D-5 L were compared with those of the WHOQOL-BREF to test the convergent validity (constructs measuring the same concept) and divergent validity (constructs measuring different concepts) of the EQ-5D-5 L. Repeated surveys were conducted on 271 participants to determine the test–retest reliability of the EQ-5D-5 L. Results The four physical dimensions (mobility, self-care, usual activities, and pain/discomfort) of the EQ-5D-5 L had moderate or high correlations with the physical health domain of the WHOQOL-BREF, with a correlation coefficient (r) ranging from 0.459 to 0.559. The anxiety/depression dimension of the EQ-5D-5 L had a high correlation (r = 0.667) with the psychological domain of the WHOQOL-BREF. By contrast, lower but still significant physical-to-psychological correlations were found between the two instruments (r ranging from 0.219 to 0.396). In addition, the EQ-5D-5 L dimensional scores showed no or weak correlations with the environment and social domains of the WHOQOL-BREF (r ranging from 0.016 to 0.207). High test-retest reliability (> 0.7) was evident. Conclusion The Chinese version of the EQ-5D-5 L has satisfactory reliability and validity in FCs of leukemia patients. It can be used to elicit utility of health-related quality of life in FCs of leukemia.http://link.springer.com/article/10.1186/s12885-019-5721-2LeukemiaFamily caregiverEQ-5D-5 LValidityReliability |
| spellingShingle | Limin Li Chaojie Liu Xiuzhi Cai Hongjuan Yu Xueyun Zeng Mingjie Sui Erwei Zheng Yang Li Jiao Xu Jin Zhou Weidong Huang Validity and reliability of the EQ-5D-5 L in family caregivers of leukemia patients BMC Cancer Leukemia Family caregiver EQ-5D-5 L Validity Reliability |
| title | Validity and reliability of the EQ-5D-5 L in family caregivers of leukemia patients |
| title_full | Validity and reliability of the EQ-5D-5 L in family caregivers of leukemia patients |
| title_fullStr | Validity and reliability of the EQ-5D-5 L in family caregivers of leukemia patients |
| title_full_unstemmed | Validity and reliability of the EQ-5D-5 L in family caregivers of leukemia patients |
| title_short | Validity and reliability of the EQ-5D-5 L in family caregivers of leukemia patients |
| title_sort | validity and reliability of the eq 5d 5 l in family caregivers of leukemia patients |
| topic | Leukemia Family caregiver EQ-5D-5 L Validity Reliability |
| url | http://link.springer.com/article/10.1186/s12885-019-5721-2 |
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